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Erythromycin ethylsuccinate

Basic information Safety Supplier Related

Erythromycin ethylsuccinate Basic information

Product Name:
Erythromycin ethylsuccinate
Synonyms:
  • ERYTHROMYCIN 2'-(ETHYL BUTANEDIOATE)
  • ERYTHROMYCIN 2'-(ETHYL SUCCINATE)
  • ERYTHROMYCIN ETHYLSUCCINATE
  • erythrocinethylsuccinate
  • erythromycin,mono(ethylsuccinate)
  • erythromycin,mono(ethylsuccinate)(ester)
  • Succinic acid, monoester with erythromycin
  • Erythromycin 2''-[3-(ethoxycarbonyl)propionate]
CAS:
1264-62-6
MF:
C43H75NO16
MW:
862.05
EINECS:
215-033-8
Product Categories:
  • ERYPED
  • Organics
  • Interferes with Protein SynthesisAntibiotics
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Chemical Structure Class
  • Macrolides
  • Mechanism of Action
  • Spectrum of Activity
Mol File:
1264-62-6.mol
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Erythromycin ethylsuccinate Chemical Properties

Melting point:
219-224 C
Boiling point:
778.19°C (rough estimate)
Density 
1.1417 (rough estimate)
refractive index 
1.5280 (estimate)
Flash point:
>110°(230°F)
storage temp. 
2-8°C
solubility 
ethanol: soluble50mg/mL
pka
13.09±0.70(Predicted)
form 
solid
color 
white
Water Solubility 
Freely soluble in organic solvents, practically insoluble in water
CAS DataBase Reference
1264-62-6
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
42/43-36/37/38
Safety Statements 
36-26
WGK Germany 
2
RTECS 
WM9800000
HS Code 
29419000
Hazardous Substances Data
1264-62-6(Hazardous Substances Data)
Toxicity
LD50 oral in mouse: > 10gm/kg

MSDS

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Erythromycin ethylsuccinate Usage And Synthesis

Chemical Properties

ERYTHROMYCIN ETHYLSUCCINATE is crystals

Uses

antibacterial

brand name

E-Mycin (Pharmacia & Upjohn); E.E.S. (Abbott); Eryped (Abbott); Pediamycin (Ross); Wyamycin (Wyeth).

General Description

Erythromycin ethylsuccinate (EES, Pediamycin, EryPed) isthe ethylsuccinate mixed ester of erythromycin in which the2'-hydroxyl group of the desosamine is esterified. It isabsorbed as the ester and hydrolyzed slowly in the body toform erythromycin. It is somewhat acid labile, and itsabsorption is enhanced by the presence of food. The ester isinsoluble in water but soluble in alcohol and ether.

Erythromycin ethylsuccinate Preparation Products And Raw materials

Raw materials

Erythromycin ethylsuccinate Supplier

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