6-HYDROXYFLAVANONE
6-HYDROXYFLAVANONE Basic information
- Product Name:
- 6-HYDROXYFLAVANONE
- Synonyms:
-
- HYDROXYFLAVANONE, 6-
- 6'-HYDROXYFLAVANONE
- 6-HYDROXYFLAVANONE
- 2-Phenyl-6-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one
- 6-OH Flavanone
- 6-hydroxy-2-phenylchroMan-4-one
- 6-Hydroxyflavanone 99%
- 6-Hydroxyflavanone,98+%
- CAS:
- 4250-77-5
- MF:
- C15H12O3
- MW:
- 240.25
- EINECS:
- 624-472-8
- Product Categories:
-
- Flavanones
- Biochemistry
- Flavonoids
- Benzopyrans
- Building Blocks
- Heterocyclic Building Blocks
- Mol File:
- 4250-77-5.mol
6-HYDROXYFLAVANONE Chemical Properties
- Melting point:
- 220-222 °C (dec.) (lit.)
- Boiling point:
- 464.3±45.0 °C(Predicted)
- Density
- 1.288±0.06 g/cm3(Predicted)
- pka
- 9.53±0.40(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- BRN
- 87354
- LogP
- 2.955 (est)
- CAS DataBase Reference
- 4250-77-5(CAS DataBase Reference)
MSDS
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
6-HYDROXYFLAVANONE Usage And Synthesis
Chemical Properties
Slightly yellow-cream powder
Uses
6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.
Definition
ChEBI: A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6.
General Description
6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.
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6-HYDROXYFLAVANONE(4250-77-5)Related Product Information
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- FLAVANONE
- DIHYDROOROXYLIN
- 6,2'',4''-TRIMETHOXYFLAVANONE
- 6,2'-DIHYDROXYFLAVANONE
- 3'-HYDROXYFLAVANONE,HYDROXYFLAVANONE, 3'