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7-DEAZA-7-IODO-2'-DEOXYGUANOSINE

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7-DEAZA-7-IODO-2'-DEOXYGUANOSINE Basic information

Product Name:
7-DEAZA-7-IODO-2'-DEOXYGUANOSINE
Synonyms:
  • 7-Deaza-2'-deoxy-7-iodoguanosine
  • 7-Deaza-7-I-2'-dA
  • 7-Deaza-21-deoxy-7-iodoguanosine
  • 7-Deaza-7-I-2'-dG
  • 7-Deaza-7-Iodo-2'-DeoxyGuanosine, >98%
  • 2-AMino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-5-iodo-1H-pyrrolo[2,3-d]pyriMidin-4(7H)-one
  • 2-amino-7-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodo-3H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
  • 7-iodo-7-deaza-2'-deoxyguanosine
CAS:
172163-62-1
MF:
C11H13IN4O4
MW:
392.15
EINECS:
2017-001-1
Mol File:
Mol File
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7-DEAZA-7-IODO-2'-DEOXYGUANOSINE Chemical Properties

Melting point:
>170oC (dec.)
Density 
2.49±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, Heated, Sonicated)
form 
Solid
pka
10.28±0.20(Predicted)
color 
White to Off-White
InChI
InChI=1S/C11H13IN4O4/c12-4-2-16(7-1-5(18)6(3-17)20-7)9-8(4)10(19)15-11(13)14-9/h2,5-7,17-18H,1,3H2,(H3,13,14,15,19)/t5-,6+,7+/m0/s1
InChIKey
TVQBNMOSBBMRCZ-RRKCRQDMSA-N
SMILES
C12N=C(N)NC(=O)C=1C(=CN2[C@H]1C[C@@H]([C@@H](CO)O1)O)I
CAS DataBase Reference
172163-62-1
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7-DEAZA-7-IODO-2'-DEOXYGUANOSINE Usage And Synthesis

Uses

7-Iodo-7-deaza-2'-deoxyguanosine (7-Deaza-7-Iodo-2'-deoxyguanosine) is a deoxyguanosine derivative that can be used in DNA synthesis and sequencing reactions[1].

References

[1] Ronald Graham, et al. Nucleotide cleavable linkers and uses thereof. WO2020146397A1.

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