N-Acetylmorpholine Chemical Properties

Melting point:

14 °C (lit.)

Boiling point:

240-245 °C

Density 

1.116 g/mL at 25 °C (lit.)

vapor pressure 

2.2Pa at 20℃

refractive index 

n20/D 1.483(lit.)

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

form 

clear liquid

pka

-0.72±0.20(Predicted)

Specific Gravity

1.116

color 

Colorless to Light yellow

Water Solubility 

MISCIBLE

BRN 

111971

LogP

-0.81 at 24℃

CAS DataBase Reference

1696-20-4(CAS DataBase Reference)

NIST Chemistry Reference

Morpholine, 4-acetyl-(1696-20-4)

EPA Substance Registry System

Morpholine, 4-acetyl- (1696-20-4)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36-62-43

Safety Statements 

26-36-39-36/37

WGK Germany 

1

RTECS 

QD7000000

TSCA 

Yes

HS Code 

29349990

MSDS

• Language:English Provider:4-Acetylmorpholine
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

N-Acetylmorpholine Usage And Synthesis

Uses

N-Acetylmorpholine is a very important pesticide intermediate. It is one of the main raw materials for the synthesis of agricultural fungicides enoylmorpholine and flumorpholine.

Chemical Properties

CLEAR COLOURLESS TO VERY SLIGHTLY YELLOW LIQUID

Application

N-acetylmorpholine is a kind of oxaza compound mainly used to synthesize medical disinfectant use in agriculture, Aromatics Extractive Project agents, and gas sweetening agents.

Flammability and Explosibility

Non flammable

Synthesis

Acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine, the first step generates alkylbenzyldimethylasaltsum salts and a strong exothermal reaction; both can carry out under normal temperature, the alkylbenzyldimethylasaltsum saltsum of generation is solid; The dehydration of second step alkylbenzyldimethylasaltsum saltsum generates N-acetyl morphine, is thermo-negative reaction, need at high temperature to carry out, and speed of response is slow. The rate-determining steps of acetic acid and morpholine Reactive Synthesis N-Acetylmorpholine are morpholine dehydration of salt, and high temperature and in time dehydration are favorable to raising the speed of response.

Purification Methods

Distil it through an 8inch Fenske (glass helices packing, p 11) column with a manual take-off head. Purify it by fractional distillation. The hydrobromide has m 172-175o. [Brace J Am Chem Soc 75 357 1953, deBenneville et al. J Org Chem 21 1072 1956, Beilstein 27 III/IV 274.]

N-Acetylmorpholine(1696-20-4)Related Product Information

• Moroxydine
• Dimethomorph
• Moroxydine hydrochloride
• N-ACETYL-L-TYROSINE ETHYL ESTER
• nicopholine
• N-ACETOACETYLMORPHOLINE
• N-CYANOACETYLMORPHOLINE
• N-DECANOYLMORPHOLINE
• 4-[2-(PIPERAZIN-1-YL)-ACETYL]-MORPHOLINE
• 4-Acryloylmorpholine
• trimetozine
• 4-(Trifluoroacetyl)morpholine
• 4-(2-CHLOROACETYL)MORPHOLINE
• N-METHACRYLOYLMORPHOLINE
• (2-AMINO-PHENYL)-MORPHOLIN-4-YL-METHANONE
• MORPHOLINOACETMORPHOLIDE
• (2-CHLORO-PHENYL)-MORPHOLIN-4-YL-METHANONE
• N-SALICYLOYL MORPHOLINE