5,7-Dihydroxy-4-methylcoumarin Chemical Properties

Melting point:

296-299 °C (lit.)

Boiling point:

472.1±14.0 °C(Predicted)

Density 

1.456±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

7.29±0.20(Predicted)

color 

Off-White to Pale Green

λmax

322nm(MeOH)(lit.)

Sensitive 

Light Sensitive

BRN 

179133

InChIKey

QNVWGEJMXOQQPM-UHFFFAOYSA-N

CAS DataBase Reference

2107-76-8(CAS DataBase Reference)

EPA Substance Registry System

5,7-Dihydroxy-4-methylcoumarin (2107-76-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

TSCA 

Yes

HazardClass 

IRRITANT

HS Code 

29321900

Hazardous Substances Data

2107-76-8(Hazardous Substances Data)

MSDS

• Language:English Provider:5,7-Dihydroxy-4-methylchromen-2-one
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

5,7-Dihydroxy-4-methylcoumarin Usage And Synthesis

Chemical Properties

White metallic powder

Uses

5,7-Dihydroxy-4-methylcoumarin may be used in the synthesis of pyrano[2,3-h]coumarin derivatives and 5,7-dihydroxy-8-formyl-4-methylcoumarin.

Definition

ChEBI: 5,7-Dihydroxy-4-methylcoumarin is a hydroxycoumarin.

General Description

Yellow powder. Fluoresces blue. Absorbs ultraviolet light.

Air & Water Reactions

Slightly water soluble .

Reactivity Profile

5,7-Dihydroxy-4-methylcoumarin is a phenol and lactone. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Lactones react similarly to esters. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Fire Hazard

Flash point data for 5,7-Dihydroxy-4-methylcoumarin are not available. 5,7-Dihydroxy-4-methylcoumarin is probably combustible.

5,7-Dihydroxy-4-methylcoumarin(2107-76-8)Related Product Information

• 6-Methylcoumarin
• Dihydrocoumarin
• Esculetin
• 6-Hydroxycoumarin
• Butylated Hydroxytoluene
• 1-Hydroxyethylidene-1,1-diphosphonic acid
• 4-Methylumbelliferone
• 4-HYDROXY MEPHENYTOIN
• 1,3-Dihydroxyacetone
• Triclosan
• Coumarin 120
• 4-Methylcumarin
• Coumarin
• Chrysin
• 7-Hydroxycoumarin
• Solvent Red 43
• 4-Hydroxycoumarin
• 7,8-DIHYDROXY-4-METHYLCOUMARIN