1-Chlorododecane Chemical Properties

Melting point:

-9.3 °C

Boiling point:

260 °C

Density 

0.867 g/mL at 20 °C (lit.)

vapor pressure 

55.2-316.9hPa at 162.35-216.25℃

refractive index 

n20/D 1.443

Flash point:

130 °C

storage temp. 

Store below +30°C.

solubility 

<0.007g/l

form 

Liquid

color 

Clear colorless

Water Solubility 

0.0068 g/L (20 ºC)

FreezingPoint 

-9.3℃

BRN 

635778

Dielectric constant

4.1699999999999999

InChIKey

YAYNEUUHHLGGAH-UHFFFAOYSA-N

LogP

6.49 at 25℃

CAS DataBase Reference

112-52-7(CAS DataBase Reference)

NIST Chemistry Reference

Dodecane, 1-chloro-(112-52-7)

EPA Substance Registry System

Dodecane, 1-chloro- (112-52-7)

Safety Information

Hazard Codes 

Xn,N,Xi

Risk Statements 

40-50/53-38-66

Safety Statements 

24-36/37-60-61-37-46

RIDADR 

UN 3082 9/PG 3

WGK Germany 

3

HazardClass 

9

PackingGroup 

III

HS Code 

29031980

HS Code 

29189090

MSDS

• Language:English Provider:1-Chlorododecane
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

1-Chlorododecane Usage And Synthesis

Chemical Properties

Colorless liquid. Insoluble in water, soluble in benzene, soluble in ethanol.

Uses

1-Chlorododecane is used as a reagent in the chemical modification of zein to reduce the brittleness of zein films. It also used as a solvent and in the manufacture of photographic chemicals, pharmaceuticals, organometallic compounds, and surfactants.

Application

Lauroyl chloride is an important organic intermediate and is widely used in the synthesis of surfactants, and it is also used in the synthesis of rubber scorch retardant, medicine and pesticide.

Preparation

500 ml round-bottomed flask fitted with a double surface condenser and charged with 109.5 ml (or 179 grams) of freshly distilled thionyl chloride, and 46.5 grams of n-dodecyl alcohol (lauryl alcohol) are slowly added during 2 hours. When all the n-dodecyl alcohol has been added, the reaction mixture is refluxed for 6 hours. The obtained reaction mixture is distilled and the excess of thionyl chloride passes over below 80° C, followed by a small fraction up to 120° C. Finally, the crude 1-chlorododecane distills at 252-257° C, mainly at 255-257° C. The purified 1-chlorododecane is washed with water, 10% sodium carbonate solution, twice with water and dried with anhydrous calcium chloride. 1-Chlorododecane is additionally purified by distillation through an efficient fractionating column. Pure n-hexyl chloride passes over at 116.5° C/5 mm. The yield is 35 grams.

Synthesis Reference(s)

Synthesis, p. 746, 1980 DOI: 10.1055/s-1980-29199

General Description

Lauryl chloride is a clear colorless oily liquid. (NTP, 1992)

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1-Chlorododecane may be incompatible with strong oxidizing and reducing agents. May be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Fire Hazard

1-Chlorododecane is combustible.

1-Chlorododecane(112-52-7)Related Product Information

• 1-Chlorooctadecane
• 1-Chlorohexadecane
• DODECANEDIOYL DICHLORIDE
• Palmitoyl chloride
• Lauroyl chloride
• Cholesteryl chloride
• 1-CHLORODOCOSANE
• STEAROYL CHLORIDE
• 1-Chlorotetradecane
• Myristoyl chloride
• 1-Chlorododecane
• Chlormadinone acetate
• 1,12-DICHLORODODECANE
• BEHENOYL CHLORIDE
• PENTADECANOYL CHLORIDE
• KELEVAN
• METHYL DICHLOROSTEARATE
• NONADECANOYL CHLORIDE
• Dodecyl Chloride