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D(-)Prolinol

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D(-)Prolinol Basic information

Product Name:
D(-)Prolinol
Synonyms:
  • (+)-D-PROLINOL
  • D(-)PROLINOL
  • D-PROLINOL
  • H-D-PROLINOL
  • H-D-PRO-OL
  • (R)-(-)-2-(Hydroxymethyl)pyrrolidine (R)-(-)-2-Pyrrolidinemethanol
  • (R)-(-)-PyrrolidinemethanolD-Prolinol
  • D-Pro-ol(oil)
CAS:
68832-13-3
MF:
C5H11NO
MW:
101.15
EINECS:
629-147-4
Product Categories:
  • Amino alcohols
  • Chiral Building Blocks
  • Proline [Pro, P]
  • Amino Alcohols
  • Glycidyl Compounds, etc. (Chiral)
  • Synthetic Organic Chemistry
  • Pharmaceutical Intermediates
Mol File:
68832-13-3.mol
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D(-)Prolinol Chemical Properties

alpha 
-31 º (c=1, toluene)
Boiling point:
74-76 °C2 mm Hg(lit.)
Density 
1.036 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.485
Flash point:
187 °F
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly), Toluene (Slightly)
pka
14.77±0.10(Predicted)
form 
Solution
color 
Clear to slightly hazy colorless to amber
Specific Gravity
1.025
optical activity
[α]20/D 31°, c = 1 in toluene
Sensitive 
Air Sensitive
BRN 
1523669
InChIKey
HVVNJUAVDAZWCB-RXMQYKEDSA-N
CAS DataBase Reference
68832-13-3(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-26/36
RIDADR 
NA 1993 / PGIII
WGK Germany 
3
3-10-23
Hazard Note 
Irritant/Air Sensitive
HazardClass 
IRRITANT
HS Code 
29339900

MSDS

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D(-)Prolinol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(2R)-2-Pyrrolidinemethanol is used in the synthesis of potent selective 5-HT7 antagonists.

Definition

ChEBI: The D-enantiomer of prolinol. Metabolite observed in cancer metabolism.

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