6-Fluoroindole Chemical Properties

Melting point:

72-76 °C (lit.)

Boiling point:

230°C (rough estimate)

Density 

1.1203 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

Crystalline Powder

pka

16.40±0.30(Predicted)

color 

Beige-brown

Water Solubility 

Insoluble

Sensitive 

Light Sensitive

BRN 

112192

InChI

InChI=1S/C8H6FN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H

InChIKey

YYFFEPUCAKVRJX-UHFFFAOYSA-N

SMILES

N1C2=C(C=CC(F)=C2)C=C1

CAS DataBase Reference

399-51-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

F 

10

HazardClass 

IRRITANT

HS Code 

29339900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

6-Fluoroindole Usage And Synthesis

Chemical Properties

beige-brown crystalline powder

Uses

6-Fluoroindole acts as a reagent in the synthesis of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, which acts as a potential anticancer immunomodulator. It is also employed as an antifungal and antibacterial agent. Further, it serves as a potent selective serotonin reuptake inhibitor. In addition to this, it is used as a inhibitor of HIV-1 attachment.

General Description

6-Fluoroindole is a halogen substituted indole. Experimental ionization potential of 6-fluoroindole has been evaluated. Preparation of 6-fluoroindole via nitration of indoline has been reported.

6-Fluoroindole(399-51-9)Related Product Information

• Indole-3-acetic acid
• Indole-3-butyric acid
• Indometacin
• Indoline
• Indole
• Tiflucarbine
• Fluorine
• 6-FLUOROINDOLE-3-ACETIC ACID
• 6-FLUORO-DL-TRYPTOPHAN
• 6-Fluorotryptamine hydrochloride
• 6-FLUOROINDOLE-3-CARBOXALDEHYDE 98% (HPLC),6-FLUOROINDOLE-3-ALDEHYDE,6-FLUOROINDOLE-3-CARBALDEHYDE,6-FLUOROINDOLE-3-CARBOXALDEHYDE
• 5-Fluoro-2,3-dimethyl-1H-indole
• 5-Fluoroindoline
• 6-Fluoro-2-oxindole
• 4,6-DIFLUOROOXINDOLE
• 5-Fluorotryptamine hydrochloride
• 5-Fluoroindole-2-carboxylicacid,99%,5-Fluoroindole-2-carboxylic acid 99%
• 1-Boc-5-fluoroindole-2-boronic acid