CRF (HUMAN, RAT) Chemical Properties

storage temp. 

−20°C

solubility 

H2O : 16.66 mg/mL (3.50 mM; Need ultrasonic and warming)

form 

White to off-white lyophilized solid

Water Solubility 

Soluble to 1.10 mg/ml in water

Safety Information

WGK Germany 

3

RTECS 

GM7925000

F 

10

HS Code 

2937190000

MSDS

• Language:English Provider:SigmaAldrich

CRF (HUMAN, RAT) Usage And Synthesis

Uses

Treatment of symptoms associated with peritumoral edema in brain tumor patients.

Uses

Corticotropin Releasing Factor human, rat has been used:

• as a component in Dulbecco′s modified eagle medium (DMEM) for incubating lung explants
• as a component in serum-free complete medium for isolation and culturing of fetal distal lung epithelial cells
• in the synthesis of the corticotropin-releasing factor(CRF)-TAMRA?1?mixture
• in chronic intracerebroventicular administration, to study its effect on hypoxia in hippocampus

brand name

Xerecept (Hollister-Stier) [Note—The source of the product (human, porcine, etc.) must be indicated in the labeling.].

General Description

Corticotropin-releasing factor is a 41-amino-acid polypeptide. It is expressed in neurons, hypothalamus?and amygdala.

Biochem/physiol Actions

CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.

storage

Store at -20°C

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