METHYLSULFONYLACETONE Chemical Properties

Melting point:

48-52 °C (lit.)

Boiling point:

300.8±25.0 °C(Predicted)

Density 

1.208±0.06 g/cm3(Predicted)

Flash point:

>230 °F

storage temp. 

2-8°C

form 

powder or crystals

Water Solubility 

Insoluble in water.

BRN 

1754113

CAS DataBase Reference

5000-46-4(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

HS Code 

29302000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

METHYLSULFONYLACETONE Usage And Synthesis

Uses

Methylsulfonylacetone is used as reactant for Stereoselective preparation of chiral cyclic ketones. It is used in the Preparation of poly-substituted pyridines. It aids for Gold-catalyzed Friedlander cyclocondensation reaction. It is used as reactant in Radical homoallylation reactions, multicomponent cyclocondensation with aldehydes and aminoazoles.

General Description

Methanesulfonylacetone is a sulfonyl group-containing active methylene compound. It can react with Baylis–Hillman acetates in dimethylformamide/potassium carbonate system to form ortho-hydroxyacetophenone derivatives.

METHYLSULFONYLACETONE(5000-46-4)Related Product Information

• METHYLSULFONYLACETONE
• 4-CHLOROPHENYLSULFONYLACETONE
• 1-(4'-CHLOROBENZENESULFONYL)-3,3-DIMETHYLBUTANE-2-ONE
• 2-(P-TOLUENESULFONYL)ACETOPHENONE
• 2-(PHENYLSULFONYL)ACETOPHENONE
• 2,5-DIPHENYL-4-HYDROXY-3-OXO-2,3-DIHYDROTHIOPHENE 1,1-DIOXIDE
• 4-TOLUENESULFONYLACETONE
• BENZENESULFONYLACETONE
• 1-(4-TOLUENESULPHONYL)-3,3-DIMETHYLBUTANE-2-ONE
• 3-((4-CHLOROPHENYL)SULFONYL)-4-ETHOXYBUT-3-EN-2-ONE
• 4'-METHYL-2(P-TOLYL SULFONYL)ACETOPHENONE
• 3-CHLORO-1-((4-METHYLPHENYL)SULFONYL)ACETONE
• 2-METHYLSULFONYLACETOPHENONE
• 1-(4-CHLOROPHENYL)-2-[(4-CHLOROPHENYL)SULFONYL]-1-ETHANONE
• 1-(4-METHOXYPHENYL)-2-(PHENYLSULFONYL)-1-ETHANONE
• 2-PROPANONE, 1-[(4-METHOXYPHENYL)SULFONYL]-
• 3-Chloro-1-phenylsulfonyl-2-propanone
• 1-(4-CHLORO-3-METHYLPHENYL)-2-((4-METHYLPHENYL)SULFONYL)ETHAN-1-ONE