5-BROMOISOPHTHALALDEHYDE Chemical Properties

Boiling point:

307.1±27.0 °C(Predicted)

Density 

1.652±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

solid

color 

Off-white

InChI

InChI=1S/C8H5BrO2/c9-8-2-6(4-10)1-7(3-8)5-11/h1-5H

InChIKey

QAQOLRCTTDVBAK-UHFFFAOYSA-N

SMILES

C1(C=C(Br)C=C(C=O)C=1)C=O

Safety Information

HS Code 

2913000090

5-BROMOISOPHTHALALDEHYDE Usage And Synthesis

Synthesis

General procedure for the synthesis of 5-bromoisophthalaldehyde from 5-bromo-1,3-dihydroxymethylbenzene: Manganese(IV) dioxide (35.5 g, 408 mmol) was added to a solution of 5-bromo-1,3-phenylenedimethanol (3.60 g, 16.6 mmol) in tetrahydrofuran (250 mL) and the reaction was heated for 4 hr at 60 °C. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the filtrate was concentrated under reduced pressure to remove the solvent. The final 5-bromoisophthalaldehyde (1.61 g, 46% yield) was obtained as a white solid.

References

[1] Tetrahedron Letters, 2000, vol. 41, # 7, p. 1015 - 1018
[2] Synthesis, 1998, # 12, p. 1742 - 1749
[3] Chemische Berichte, 1989, vol. 122, p. 1365 - 1372
[4] New Journal of Chemistry, 2009, vol. 33, # 2, p. 345 - 357
[5] Patent: JP2015/224231, 2015, A. Location in patent: Paragraph 0071

5-BROMOISOPHTHALALDEHYDE(120173-41-3)Related Product Information

• 5-BROMOISOPHTHALIC ACID
• 5-Bromo-1,3-benzenediol
• 5-Bromo-1,3-phenylenediamine
• DIETHYL 5-BROMOISOPHTHALATE
• 1,3-DiaMino-5-broMobenzene
• Ipratropium bromide monohydrate
• DIMETHYL 5-BROMOISOPHTHALATE
• 1-Piperidinecarbothioamide, N-[3-(2,4,6-trichlorophenoxy)-1-propyn-1-yl]-
• 5-TERT-BUTYL METHYLISOPHTHALATE
• 5-BROMOISOPHTHALALDEHYDE
• 4-BROMO-1-HYDROXYANTHRAQUINONE-2-CARBOXYLIC ACID
• 1-amino-4-bromo-9,10-dioxo-9,10-dihydroan thracene-2-carboxylic acid
• 2-BROMO-5,7-DINITRO-4-CARBOXYLIC ACID-9-FLUORENONE
• 2,7-DIBROMO-4-CARBOXYLIC ACID-5-NITRO-9-FLUORENONE
• AKOS BC-1724
• 4-BROMO-2,6-BIS(TRIFLUOROACETYL)PHENOL
• 2,7-DIBROMO-4-CARBOXYL-9-FLUORENONE
• METHYL-2,7-DIBROMO-9-FLUORENONE-4-CARBOXYLATE