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N-(m-PEG4)-N'-(biotin-PEG3)-Cy5

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N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 Basic information

Product Name:
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5
Synonyms:
  • N-(m-PEG4)-N'-(biotin-PEG3)-Cy5
CAS:
2107273-68-5
MF:
C52H76ClN5O9S
MW:
982.72
Mol File:
2107273-68-5.mol
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N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 Chemical Properties

solubility 
Soluble in Water, DMSO, DMF, DCM
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N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 Usage And Synthesis

Description

N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm as well as biotin, which enables efficient protein enrichment. The hydophilic PEG spacer increases solubility in aqueous media.

Uses

N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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