3-Mercaptopropionic acid Chemical Properties

Melting point:

15-18 °C (lit.)

Boiling point:

110-111 °C/15 mmHg (lit.)

Density 

1.218 g/mL at 25 °C (lit.)

vapor pressure 

0.04 mm Hg ( 20 °C)

refractive index 

n20/D 1.492(lit.)

FEMA 

4587 | 3-MERCAPTOPROPIONIC ACID

Flash point:

201 °F

storage temp. 

Store below +30°C.

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

pka

pK1:;pK2:10.84(SH) (25°C)

form 

Crystalline Powder, Crystals, and/or Chunks

color 

White

Specific Gravity

1.218

PH

2 (120g/l, H2O, 20℃)

Odor

sulfurous roasted

Odor Type

sulfurous

explosive limit

1.60%(V)

Water Solubility 

soluble

Sensitive 

Air Sensitive & Hygroscopic

JECFA Number

1936

BRN 

773807

Stability:

Air Sensitive, Hygroscopic

InChIKey

DKIDEFUBRARXTE-UHFFFAOYSA-N

LogP

-2.3 at 22℃

CAS DataBase Reference

107-96-0(CAS DataBase Reference)

NIST Chemistry Reference

3-Thiolpropanoic acid(107-96-0)

EPA Substance Registry System

3-Mercaptopropanoic acid (107-96-0)

Safety Information

Hazard Codes 

T

Risk Statements 

25-34-23/24/25

Safety Statements 

7-26-36/37/39-45

RIDADR 

UN 2922 8/PG 2

WGK Germany 

1

RTECS 

UF5270000

F 

10-13

Autoignition Temperature

662 °F

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29309070

Hazardous Substances Data

107-96-0(Hazardous Substances Data)

Toxicity

LD50 orally in Rabbit: 96 mg/kg

MSDS

• Language:English Provider:3-Mercaptopropionic acid
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3-Mercaptopropionic acid Usage And Synthesis

Chemical Properties

clear colourless to yellowish liquid after melting

Uses

A compound suitable for amino acid analysis by means of OPA

Uses

3-Mercaptopropionic acid is widely used in food and beverage industries as a flavoring agent. It is used in the production of PVC stabilizers, which are used as chain transfer agents in polymerizations. It can be used as primary or secondary, color stabilizer in combination with phenolic antioxidant for polymers. It acts as a sulfide ion equivalent and is utilized in the preparation of diaryl sulfide from aryl iodide.

Definition

ChEBI: A mercaptopropanoic acid that is propanoic acid carrying a sulfanyl group at position 3.

General Description

3-Mercaptopropionic acid (3-MPA) is used as a self-assembled monolayer (SAM) with a thiol and carboxylic groups. It has short carbon chains and is mainly used as a capping agent on a variety of nanoparticles.

Biological Activity

3-Mercaptopropionic acid is a blocking drug that causes an increase in sleep and a decrease in wakefulness. A related finding is that nipecotic acid also increases the time needed for isoflurane to induce loss of consciousness, whereas 3-mercaptopropionic acid decreases anesthesia induction time[1].

References

[1] Thakkar, M. and R. McCarley. “Neurochemistry of Sleep and Wakefulness: Histamine in the control of sleep–wakefulness.”Basic Neurochemistry (Eighth Edition) (2012).

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