3,4-Dichlorophenol Chemical Properties

Melting point:

65-67 °C(lit.)

Boiling point:

145-146 °C(lit.)

Density 

1.3446 (rough estimate)

refractive index 

1.4430 (estimate)

Flash point:

252-255°C

storage temp. 

0-6°C

solubility 

9260mg/l (experimental)

form 

Powder

pka

pK1:8.630 (25°C)

color 

White to brownish

Water Solubility 

<0.1 g/100 mL at 20 ºC

BRN 

1907693

Stability:

Stable. Combustible. Incompatible with oxidizing agents, acid chlorides, acid anhydrides.

InChIKey

WDNBURPWRNALGP-UHFFFAOYSA-N

CAS DataBase Reference

95-77-2(CAS DataBase Reference)

NIST Chemistry Reference

Phenol, 3,4-dichloro-(95-77-2)

EPA Substance Registry System

3,4-Dichlorophenol (95-77-2)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/38

Safety Statements 

26-28-37/39

RIDADR 

UN 2020 6.1/PG 3

WGK Germany 

3

RTECS 

SK8800000

Hazard Note 

Irritant

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29081000

Hazardous Substances Data

95-77-2(Hazardous Substances Data)

MSDS

• Language:English Provider:3,4-Dichlorophenol
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3,4-Dichlorophenol Usage And Synthesis

Chemical Properties

light yellow to brown crystals

Uses

3,4-Dichlorophenol (3,4-DCP) is used in the synthesis of (Z)-5-arylmethylidene rhodanines as anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. It can also be used in the preparation of 2-(3,4-dichlorophenoxy)-N-(2-morpholin-4-ylethyl)acetamide for the treatment of inflammatory pain.

Definition

ChEBI: 3,4-Dichlorophenol is a dichlorophenol.

General Description

Needles (from benzene, petroleum ether) or light brown and yellow crystals. Odor threshold 100 μg/L. Taste threshold 0.3 μg/L in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3,4-Dichlorophenol is incompatible with acid chlorides, acid anhydrides and oxidizing agents.

Fire Hazard

Flash point data for 3,4-Dichlorophenol are not available. 3,4-Dichlorophenol is probably combustible.

Purification Methods

Crystallise 3,4-dichlorophenol from pet ether/*benzene mixture and/or distil it. [Beilstein 6 IV 952.]

3,4-Dichlorophenol(95-77-2)Related Product Information

• Thionyl chloride
• PHENOLDISULFONIC ACID
• 2',4'-Dichloroacetophenone
• Dichloroethane
• 2,4-Dichlorobenzoic acid
• Sodium dichloroisocyanurate
• 1,2-Dichloro-4-(chloromethyl)benzene
• 2,3,4,6-TETRACHLOROPHENOL
• 2,3,4-TRICHLOROANISOLE
• Pentachlorophenol
• Hexachlorophene
• 2,5-Dichlorophenol
• 2,6-DICHLOROPHENOL extrapure
• 2,3-DICHLOROPHENOL 99+%
• 3,5-DICHLOROPHENOL TYPICALLY 99%
• 3,4-D
• 2,3,4-TRICHLOROPHENOL
• 2,4-DICHLOROPHENOL pract,2,4-DICHLOROPHENOL 99+%