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(R)-Duloxetine

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(R)-Duloxetine Basic information

Product Name:
(R)-Duloxetine
Synonyms:
  • (r)-duloxetine
  • (r)-n-methyl-gama-(1-naphthalenyloxy)-2-thiophenepropanamine
  • R-DULOXETINE HCL
  • N-methyl-3-(1-naphthalenyloxy)-3-thiophen-2-yl-1-propanamine
  • Ariclaim
  • CYMBALTA; ARICLAIM
  • 2-Thiophenepropanamine, N-methyl-γ-(1-naphthalenyloxy)-, (γR)
  • "(R)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan
CAS:
116539-60-7
MF:
C18H19NOS
MW:
297.41
EINECS:
1312995-182-4
Product Categories:
  • Pharmaceutical intermediate
Mol File:
116539-60-7.mol
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(R)-Duloxetine Chemical Properties

Boiling point:
466.2±40.0 °C(Predicted)
Density 
1.158
pka
10.02±0.10(Predicted)
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(R)-Duloxetine Usage And Synthesis

Uses

(R)-Duloxetine is a dual inhibitor of serotonin and norepinephrine reuptake, effective in the treatment of emotional and physical symptoms of depression

Definition

ChEBI: (R)-duloxetine is a duloxetine. It is an enantiomer of a (S)-duloxetine.

Application

Duloxetine (duloxetine) is a third-generation antidepressant launched in 2002, and its hydrochloride is clinically used under the trade name Cymbalta (Cymbalta).

Synthesis

(R)-Duloxetine was prepared from (S)-3-N,N-dimethylamino-1-(2-thienyl)-1-propanol 67.

(R)-DuloxetineSupplier

Shanghai Longsheng chemical Co.,Ltd.
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(R)-Duloxetine(116539-60-7)Related Product Information