iofendylate Chemical Properties

Melting point:

25°C

Density 

d2020 1.240-1.263

refractive index 

nD25 1.5230-1.5280

CAS DataBase Reference

99-79-6

Safety Information

HazardClass 

IRRITANT

Hazardous Substances Data

99-79-6(Hazardous Substances Data)

Toxicity

LD50 in mice, rats (g/kg): 4.6, 19 i.p. (Steinhausen)

iofendylate Usage And Synthesis

Originator

Pantopaque,Lafayette,US,1944

Uses

Iofendylate is a compound that is used as a contrast medium.

Manufacturing Process

60 volumes of ethyl undecylenate is introduced gradually at 7° to 8°C during 35 minutes to a well-cooled mixture of 52.5 parts of aluminum chloride and 150 volumes of iodobenzene. The mixture is decomposed with cracked ice and dilute hydrochloric acid. The iodobenzene layer is washed with sodium bisulfite solution and with water, and then distilled. The composition of matter having the probable formula, ethyl 4-iodophenyl-undecylate, is a colorless liquid boiling at 196° to 198°C/1 mm, and of specific gravity of 1.26/20°C.

Therapeutic Function

Diagnostic aid (radiopaque medium)

iofendylate(99-79-6)Related Product Information

• Iodide oil
• Iodixanol
• 1-(4'-IODOPHENYL)BUTANE
• 10-PHENYLDECANOIC ACID
• 1-N-HEXYL-4-IODOBENZENE
• iofendylate
• 1-N-HEPTYL-4-IODOBENZENE
• 4-IODOPENTYLBENZENE
• 1-IODO-4-ISOPROPYLBENZENE