Xanthoxyletin
Xanthoxyletin Basic information
- Product Name:
- Xanthoxyletin
- Synonyms:
-
- Xanthoxyletin
- 5-Methoxy-8,8-dimethyl-2H,8H-benzo[1,2-b:5,4-b']dipyran-2-one
- Xanthoxylin N
- Xanthoxyloin
- 5-methoxy-8,8-dimethyl-pyrano[3,2-g]chromen-2-one
- 5-methoxy-8,8-dimethylpyrano[3,2-g]chromen-2-one
- NSC 35542
- 2H,8H-Benzo[1,2-b:5,4-b']dipyran-2-one, 5-methoxy-8,8-dimethyl-
- CAS:
- 84-99-1
- MF:
- C15H14O4
- MW:
- 258.27
- Mol File:
- 84-99-1.mol
Xanthoxyletin Chemical Properties
- Melting point:
- 134-135℃ (ethanol )
- Boiling point:
- 321.52°C (rough estimate)
- Density
- 1.1178 (rough estimate)
- refractive index
- 1.4300 (estimate)
- LogP
- 3.640 (est)
Xanthoxyletin Usage And Synthesis
Uses
Xanthoxyletin is a coumarin that can be isolated from Genus Zanthoxylum and Clausena. Xanthoxyletin has antioxidant and anti-inflammatory activities. Xanthoxyletin shows cytotoxic effects to cancer cells, and induces apoptosis and necrosis. Xanthoxyletin can be used for the research of cancer and inflammation[1][2].
Definition
ChEBI: A natural product found in Clausena harmandiana.
References
[1] Sanna MD, et al. Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. Eur J Pharmacol. 2020 Feb 5;868:172859. DOI:10.1016/j.ejphar.2019.172859
[2] Jantamat P, et al. Cytotoxicity and Apoptosis Induction of Coumarins and Carbazole Alkaloids from Clausena harmandiana. Molecules. 2019 Sep 18;24(18):3385.
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- Xanthoxyletin