ChemicalBook > Product Catalog > Pharmaceutical intermediates > Heterocyclic compound > Pyridine compound > Pyridine derivatives > Methyl 4,6-dichloronicotinate
Methyl 4,6-dichloronicotinate
Methyl 4,6-dichloronicotinate Basic information
- Product Name:
- Methyl 4,6-dichloronicotinate
- Synonyms:
-
- Methyl 4,6-dichloronicotinate
- 4,6-Dichloronicotinic acid methyl ester
- 100559
- methyl 4,6-dichloropyridine-3-carboxylate
- Methyl 4,6-dichloronicotinate 95+%
- 3-Pyridinecarboxylic acid, 4,6-dichloro-, Methyl ester
- Methyl 4,6-dichloropyridine-3-carboxylate, 2,4-Dichloro-5-(methoxycarbonyl)pyridine
- Methyl 4,6-dichloronicotinte
- CAS:
- 65973-52-6
- MF:
- C7H5Cl2NO2
- MW:
- 206.03
- Product Categories:
-
- Heterocyclic Compounds
- Pyridine
- Esters
- Pyridines
- Mol File:
- 65973-52-6.mol
More
Less
Methyl 4,6-dichloronicotinate Chemical Properties
- Melting point:
- 41-43°
- Boiling point:
- 260.0±35.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- Solid
- pka
- -1.24±0.10(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C7H5Cl2NO2/c1-12-7(11)4-3-10-6(9)2-5(4)8/h2-3H,1H3
- InChIKey
- JEJMDUMJSZTJTI-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=CC(Cl)=C1C(OC)=O
- CAS DataBase Reference
- 65973-52-6
More
Less
More
Less
Methyl 4,6-dichloronicotinate Usage And Synthesis
Uses
Methyl 4,6-dichloronicotinate could be used to synthesize 4,6-dichloronicotinic acid. Specifically, to a solution of methyl 4,6-dichloronicotinate in a mixture of THF (400 mL), MeOH (100 mL), and H2O (100 mL), a solution of NaOH (10 g) in 40 mL H2O was added. The mixture was stirred for 40 min at room temperature. Then, the solvents were reduced and acidified with concentrated HCl to a pH of about 2. It was extracted using a mixture of Et2O/EtOAc, and the organic layer was dried with Na2SO4. The solvents were removed, and the residue was dried in vacuo to obtain 4,6-dichloronicotinic acid as a white solid (12.3 g, 69% yield).
Methyl 4,6-dichloronicotinate Preparation Products And Raw materials
Preparation Products
Methyl 4,6-dichloronicotinateSupplier
Jiaxing Rich Biological Technology Co., Ltd. Gold
- Tel
- 0573-11111111-1111 18969316891
- richmol@163.com
Shandong Baiqi Biomedical Co. Ltd Gold
- Tel
- 13173160180
- sales@baiqpharm.com
Henan Junyuejian Biotechnology Co., LTD Gold
- Tel
- 1555-0142250 18661514130
- 1035729108@qq.com
J & K SCIENTIFIC LTD.
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
More
Less
Methyl 4,6-dichloronicotinate(65973-52-6)Related Product Information
- Dichlorodimethylsilane
- Sodium dichloroisocyanurate
- 5,6-Dichloronicotinic acid
- 4,6-Dichloronicotinic acid
- Methyl cellulose
- METSULFURON METHYL
- Methyl acrylate
- Quinclorac
- 2,5-Dichloronicotinic acid
- 2,6-Dichloronicotinic acid
- N,N-Dimethylacetamide
- Thionyl chloride
- 2',4'-Dichloroacetophenone
- Methanol
- Bensulfuron methyl
- Methylparaben
- Kresoxim-methyl
- Dichloroethane