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Sertaconazole nitrate

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Sertaconazole nitrate Basic information

Product Name:
Sertaconazole nitrate
Synonyms:
  • NITRATE SERTACONAZOLE
  • 1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole mononitrate
  • 1-[2-[(7-Chlorobenzo[b]thien-3-yl)Methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-iMidazole Nitrate
  • DerMovit
  • Ertaczo
  • Sertaconazole Mononitrate
  • 1H-Imidazole, 1-[2-[(7-chlorobenzo[b]thien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1)
  • SEROTONIN
CAS:
99592-39-9
MF:
C20H15Cl3N2OS.HNO3
MW:
500.78
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Inhibitors
Mol File:
99592-39-9.mol
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Sertaconazole nitrate Chemical Properties

Melting point:
158-160°
storage temp. 
-20°C
solubility 
DMSO: soluble20mg/mL, clear
form 
powder
pka
pKb: 7.26(at 25℃)
color 
white to beige
InChIKey
HAAITRDZHUANGT-UHFFFAOYSA-N
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Safety Information

WGK Germany 
3
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Sertaconazole nitrate Usage And Synthesis

Description

Sertaconazole nitrate is a new broad spectrum imidazole antifungal agent introduced in a topical formulation for the treatment of cutaneous infections. Its mechanism of action is the inhibition of ergosterol synthesis and interference with the permeability of fungus cell membranes. An oral formulation is currently under investigation for the treatment of bucco-pharyngeal fungal infections.

Chemical Properties

Off-White Solid

Originator

Ferrer (Spain)

Uses

An imidazole antifungal agent, inhibits the synthesis of ergosterol, an essential cell wall component of fungi.

Uses

Antibacterial;ergosterol synthesis inhibitor

brand name

Dermofix; Zalain

Sertaconazole nitrateSupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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LGM Pharma
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inquiries@lgmpharma.com
Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696;
Email
info@hanhongsci.com
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Sertaconazole nitrate(99592-39-9)Related Product Information