DIBROMODULCITOL Chemical Properties

Melting point:

187-188° (dec)

Boiling point:

511.2±50.0 °C(Predicted)

Density 

1.8987 (rough estimate)

refractive index 

1.4840 (estimate)

pka

12.61±0.20(Predicted)

CAS DataBase Reference

10318-26-0

EPA Substance Registry System

Mitolactol (10318-26-0)

Safety Information

Toxicity

LD50 in rats (mg/kg): 1400 orally; 470 i.p. (Kellner)

DIBROMODULCITOL Usage And Synthesis

Uses

1,6-Dibromodulcitol is an intermediate in the synthesis of Dulcitol Diepoxide (D720515). Dulcitol Diepoxide is a cytostatic drug. Dulcitol Diepoxide can be used for treatment of leukemia, lung cancer, multiple myeloma, and nasopharyngeal carcinoma.

Definition

ChEBI: Mitolactol is an alcohol and an organobromine compound.

General Description

White powder. Insoluble in water.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A halogenated alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Health Hazard

ACUTE/CHRONIC HAZARDS: DIBROMODULCITOL is toxic when ingested.

Fire Hazard

Data is not available for DIBROMODULCITOL, but DIBROMODULCITOL is probably combustible.

Safety Profile

Poison by ingestion. Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Human mutation data reported. An anti-cancer agent taken orally. When heated to decomposition it emits very toxic fumes of Br-.

DIBROMODULCITOL(10318-26-0)Related Product Information

• 4-Bromo-1-butanol
• (S)-3-Bromo-1,2-propanediol
• DIBROMODULCITOL
• 3-BROMO-1,2-PROPANEDIOL
• 1-BROMO-2-BUTANOL
• (S)-4-BROMO-1,3-BUTANEDIOL
• 5-Bromopentan-1-ol