PYR-HIS-PRO-AMC
PYR-HIS-PRO-AMC Basic information
- Product Name:
- PYR-HIS-PRO-AMC
- Synonyms:
-
- THYROTROPIN-RELEASING HORMONE-AMC
- PYR-HIS-PRO-AMC
- TRH-AMC
- PYR-HP-AMC
- L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- (9CI)
- L-Prolinamide,5-oxo-L-prolyl-L-histidyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
- TRH-AMC acetate salt Pyr-His-Pro-AMC acetate salt
- Thyrotrophin-Releasing Peptide-AMC
- CAS:
- 190836-86-3
- MF:
- C26H28N6O6
- MW:
- 520.54
- Mol File:
- 190836-86-3.mol
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PYR-HIS-PRO-AMC Chemical Properties
- Sequence
- {Pyr}-His-{Pro-AMC}
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PYR-HIS-PRO-AMC Usage And Synthesis
Uses
TRH-AMC is a fluorogenic substrate used in a coupled assay for thyrotropin-releasing hormone(TRH)-degrading ectoenzyme[1].
References
[1] Gaia A Scalabrino, et al. Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone. Neuropharmacology. 2007 Jun;52(7):1472-81. DOI:10.1016/j.neuropharm.2007.02.003
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