Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Respiratory Drugs >  Antitussives >  Eprazinone

Eprazinone

Basic information Safety Supplier Related

Eprazinone Basic information

Product Name:
Eprazinone
Synonyms:
  • EPRAZINONE
  • 1-(2-phenyl-2-ethoxy)ethyl-4-(2-benzoyl)propylpiperazine
  • β-[4-(β-Ethoxyphenethyl)-1-piperazinyl]-α-methylpropiophenone
  • 3-(4-(2-Ethoxy-2-phenylethyl)piperazin-1-yl)-2-Methyl-1-phenylpropan-1-one
  • 1-Propanone, 3-[4-(2-ethoxy-2-phenylethyl)-1-piperazinyl]-2-methyl-1-phenyl-
  • 1-(2-phenyl-2-ethoxyethyl)-4-(2-benzyloxypropyl)piperazine
  • 2-(4-(beta-ethoxyphenethyl)-1-piperazinyl)methyl-propiophenon
  • 3-(4-(2-ethoxy-2-phenylethyl)-1-piperazinyl)-2-methyl-1-phenyl-1-propano ne
CAS:
10402-90-1
MF:
C24H32N2O2
MW:
380.52
EINECS:
233-873-3
Mol File:
10402-90-1.mol
More
Less

Eprazinone Chemical Properties

Boiling point:
508.13°C (rough estimate)
Density 
1.0909 (rough estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
6.83±0.10(Predicted)
CAS DataBase Reference
10402-90-1(CAS DataBase Reference)
More
Less

Eprazinone Usage And Synthesis

Originator

Mucitux,Riom,France,1969

Definition

ChEBI: A member of the class of piperazines in which the two amino hydrogens of piperazine are replaced by 2-benzoylpropyl and 2-ethoxy-2-phenylethyl groups.

Manufacturing Process

61.4 g of 0.2M of 1-(2-phenyl-2-ethoxy)piperazine dihydrochloride, 33.5 g (0.25M) propiophenone, 75 g (0.25M) trioxymethylene, 120 ml of ethanol and 0.4 ml of concentrated HCl are heated under reflux for 4 to 5 hours. The product is allowed to crystallize, then filtered and washed with alcohol. It is dried and recrystallized from methanol containing 10% H2O.
There is thus obtained 60 g of a white crystalline powder soluble in water. Yield: 66%. Melting point: 160°C.

Therapeutic Function

Antitussive

EprazinoneSupplier

Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Email
market03@meryer.com
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Email
sales@jingyan-chemical.com
9ding chemical ( Shanghai) Limited
Tel
4009209199
Email
sales@9dingchem.com
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Email
cantotech@126.com
Finetech Industry Limited
Tel
027-87465837 19945049750
Email
sales@finetechnology-ind.com
More
Less

Eprazinone(10402-90-1)Related Product Information