ChemicalBook > Product Catalog > Biochemical Engineering > Inhibitors > protein tyrosine kinase > 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Basic information
- Product Name:
- 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
- Synonyms:
-
- 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE
- KU14R
- 1H-IMidazole,2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-
- CS-891
- KU-14R; KU 14R
- 2-(2-ethyl-3H-1-benzofuran-2-yl)-1H-imidazole
- 2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE USP/EP/BP
- CAS:
- 189224-48-4
- MF:
- C13H14N2O
- MW:
- 214.26
- Product Categories:
-
- Imidazoline binding site
- Mol File:
- 189224-48-4.mol
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2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Chemical Properties
- Boiling point:
- 428.1±34.0 °C(Predicted)
- Density
- 1.181±0.06 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- Soluble to 100 mM in DMSO
- form
- Powder
- pka
- 13.14±0.10(Predicted)
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2-(2-ETHYL-2,3-DIHYDRO-2-BENZOFURANYL)-1H-IMIDAZOLE Usage And Synthesis
Uses
KU14R is a putative imidazoline I3 receptor antagonist, which blocks the effects of the atypical I3 agonist efaroxan.
Definition
ChEBI: 2-(2-ethyl-3H-benzofuran-2-yl)-1H-imidazole is a member of 1-benzofurans.
Biological Activity
Antagonist of the atypical imidazoline binding site (putative I 3 receptor) of pancreatic β -cells. Selectively blocks efaroxan-induced insulin secretion in vitro and in vivo .
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