Basic information Safety Supplier Related

Ecabet

Basic information Safety Supplier Related

Ecabet Basic information

Product Name:
Ecabet
Synonyms:
  • Ecabet
  • 12-Sulfodehydroabietic acid
  • 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, (1R,4aS,10aR)-
  • 1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-, [1R-(1α,4aβ,10aα)]-
  • Abietic acid, dehydro-6-sulfo- (6CI)
  • Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl-12-sulfo- (8CI)
  • 13-Isopropyl-12-sulfopodocarpa-8,11,13-trien-15-oic acid
  • (1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-6-sulfo-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxylic acid
CAS:
33159-27-2
MF:
C20H28O5S
MW:
380.5
Mol File:
33159-27-2.mol
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Ecabet Chemical Properties

alpha 
D25 +72.4° (c = 2.5 in alcohol)
Density 
1.241±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
-0.31±0.60(Predicted)
InChIKey
IWCWQNVIUXZOMJ-MISYRCLQSA-N
SMILES
[C@@]1(C)(C(O)=O)[C@@]2([H])[C@@](C)(C3=C(CC2)C=C(C(C)C)C(S(O)(=O)=O)=C3)CCC1
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Ecabet Usage And Synthesis

Uses

Ecabet sodium (TA-2711) is currently applied to some clinical gastrointestinal disease by inhibiting the ROS production and improving Helicobacter pylori eradication[1]. Ecabet sodium reduces apoptosis[2]

Definition

ChEBI: Ecabet is a diterpenoid.

References

[1] Wang Y, et al. Efficacy and safety of ecabet sodium as an adjuvant therapy for Helicobacter pylori eradication: a systematic review and meta-analysis. Helicobacter. 2014 Oct;19(5):372-81. DOI:10.1111/hel.12136
[2] Rah YC, et al. Ecabet sodium alleviates neomycin-induced hair cell damage. Free Radic Biol Med. 2015 Dec;89:1176-83. PMID:265617

EcabetSupplier

Chengdu Saint - Kay Biotechnology Co., Ltd. Gold
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Beijing HuaMeiHuLiBiological Chemical
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Shanghai T&W Pharmaceutical Co., Ltd.
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Aikon International Limited
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Wuhan FengyaoTonghui Chemical Products Co., Ltd.
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