ISOPROPOXYTRIMETHYLSILANE Chemical Properties

Boiling point:

87 °C

Density 

0.745 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.378(lit.)

Flash point:

12 °F

form 

liquid

InChI

1S/C6H16OSi/c1-6(2)7-8(3,4)5/h6H,1-5H3

InChIKey

NNLPAMPVXAPWKG-UHFFFAOYSA-N

SMILES

CC(C)O[Si](C)(C)C

Safety Information

Hazard Codes 

F

Risk Statements 

11

Safety Statements 

16-36/37/39

RIDADR 

UN 1993 3/PG 2

WGK Germany 

3

HazardClass 

3.1

PackingGroup 

II

Storage Class

3 - Flammable liquids

Hazard Classifications

Flam. Liq. 2

MSDS

• Language:English Provider:SigmaAldrich

ISOPROPOXYTRIMETHYLSILANE Usage And Synthesis

Uses

ISOPROPOXYTRIMETHYLSILANE can be used in the synthesis of organosilicon compounds and also as a hydrophobic agent.

Definition

ChEBI: A silyl ether that is isopropanol in which the hydroxyl hydrogen is replaced by a trimethylsilyl group.

Synthesis

Isopropoxytrimethylsilane can be prepared from propanol, the specific method is as follows: heating system with a water bath, in the reaction vessel equipped with mechanical stirring, drop-addition device, tail gas absorption device, a strong condensation reflux device to add 1600g of hexamethyldisilazane and 40g of 731-type strong acidic styrene-based cationic resins, and then pass through nitrogen, warming to 55 C, drop-addition of 1300 g of propanol, the ammonia gas generated into the Tail gas absorption device, in the whole process of the reaction system for the micro-positive pressure, drop after the completion of the reaction at 50 ~ 60 for 5 hours, hexamethyldisilazane conversion rate of 100%, a small amount of propanol residue, the resin filtered out, the reaction solution in the product content is higher than 97%, can be used directly as a finished product, isopropoxytrimethylsilane product is 2,550 g. Yield of 88%. The process is simple, the conversion rate is high, the selectivity is good, the yield is high, and the final reaction liquid has high purity.

ISOPROPOXYTRIMETHYLSILANE(1825-64-5)Related Product Information

• 3-(tert-Butyldimethylsilyloxy)glutaric anhydride
• (3S,4R)-4-Acetoxy-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]azetidin-2-one
• DMT-2′O-TBDMS-rU Phosphoramidite
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• (3-GLYCIDOXYPROPYL)BIS(TRIMETHYLSILOXY)METHYLSILANE
• TRIMETHYLSILYLSUCROSE
• N-blocked-5'-O-DMT-2'-O-TBDMS CED cytidine phosphoramidite
• TRIMETHYLSILYL-D(+)MANNOSE
• (1-METHOXY-2-PROPOXY)TRIMETHYLSILANE
• ISOPROPOXYTRIMETHYLSILANE
• O-TRIMETHYLSILYLCHOLESTEROL
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• N2-(ISOBUTYRYL)-5'-O-(DIMETHOXYTRITYL)-2'-O-(T-BUTYLDIMETHYLSILYL)-GUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE