ACIFRAN
ACIFRAN Basic information
- Product Name:
- ACIFRAN
- Synonyms:
-
- ay25712
- ACIFRAN
- 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID
- (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
- 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
- Acifranum
- 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci
- 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid
- CAS:
- 72420-38-3
- MF:
- C12H10O4
- MW:
- 218.21
- Product Categories:
-
- Miscellaneous Compounds
- Mol File:
- 72420-38-3.mol
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ACIFRAN Chemical Properties
- Melting point:
- 176°
- Boiling point:
- 378.4±42.0 °C(Predicted)
- Density
- 1.343±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- Soluble in DMSO > 10 mM
- form
- Powder
- pka
- 2.25±0.40(Predicted)
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ACIFRAN Usage And Synthesis
Uses
Antihyperlipopro-teinemic.
Uses
Acifran is a nicotinic acid receptor agonist.
brand name
Reductol (Wyeth-Ayerst).
Biological Activity
Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.
storage
Store at +4°C
ACIFRANSupplier
3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel
- 821-50328103-801 18930552037
- 3bsc@sina.com
EMMX Biotechnology LLC
- Tel
- 888-539-0666
- info@emmx.com
Shanghai Rechem science Co., Ltd.
- Tel
- 21-31433387 15618786686
- sales@rechemscience.com
TargetMol Chemicals Inc.
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
BOC Sciences
- Tel
- info@bocsci.com