Hexahydro-4-methylphthalic anhydride Chemical Properties

Melting point:

-29°C

Boiling point:

120°C (1 mmHg)

Density 

1.162 g/mL at 25 °C(lit.)

vapor pressure 

0.23Pa at 25℃

refractive index 

n20/D 1.477(lit.)

Flash point:

>230 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Ethyl Acetate (Slightly)

form 

Liquid

pka

4.24[at 20 ℃]

color 

Clear

Water Solubility 

REACTS

Sensitive 

Moisture Sensitive

Stability:

Hygroscopic, Moisture Sensitive

InChIKey

FKBMTBAXDISZGN-UHFFFAOYSA-N

LogP

-3.95 at 20℃

CAS DataBase Reference

19438-60-9(CAS DataBase Reference)

EPA Substance Registry System

1,3-Isobenzofurandione, hexahydro-5-methyl- (19438-60-9)

Safety Information

Hazard Codes 

Xn

Risk Statements 

41-42/43

Safety Statements 

22-24-26-37/39

WGK Germany 

1

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29172090

MSDS

• Language:English Provider:MHHPA
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Hexahydro-4-methylphthalic anhydride Usage And Synthesis

Description

Methylhexahydrophthalic anhydride (MHHP A) is an epoxy hardener, irritant to skin and mucus membranes. It is included in non-diglycidyl-ether-of-bisphenol- A epoxy resins. It can induce both allergic contact dermatitis and immunologic contact urticaria. MHHP A is structurally close to methyltetrahydrophthalic anhydride (MTHP A), which can also cause sensitization.

Chemical Properties

Hexahydro-4-methylphthalic anhydride has a melting point of 29 °C, so it is a liquid at room temperature. It has a boiling point of 120 °C and at 25 °C its density is 1.162 g/mL.

Uses

Hexahydro-4-methylphthalic anhydride, mixture of?cis?and?trans may be used as an analytical standard for the determination of the analyte in human biological samples by gas chromatography-mass spectrometry (GC-MS).

General Description

Methylhexahydrophthalic anhydride, a congener of phthalic anhydride, is utilized in the production of plastics, paints, and electronic components. It can potentially result in allergenic effects on humans upon exposure and cause immunological reactions.

Flammability and Explosibility

Non flammable

Contact allergens

Methylhexahydrophthalic anhydride is an epoxy hardener, irritant to skin and mucous membranes. It is included in nondiglycidyl-ether-of-bisphenol-A epoxy resins. It can induce both allergic contact dermatitis and immunologic contact urticaria. It is structurally close to methyltetrahydrophthalic anhydride, which can also cause sensitization.

Synthesis

5-methyl-3a,4,7,7a-tetrahydroisobenzofuran-1,3-dione could used as a starting material to synthesize Hexahydro-4-methylphthalic anhydride. The byproducts include 5-methylisobenzofuran-1,3-dione, 5-methyl-4,5,6,7-tetrahydroisobenzofuran-1,3-dione, and 6-methyl-3a,4,5,7a-tetrahydroisobenzofuran-1,3-dione.

Hexahydro-4-methylphthalic anhydride(19438-60-9)Related Product Information

• 4-Methylphthalic anhydride
• CIS-BUTENEDIOIC ANHYDRIDE
• Succinic anhydride
• Methyl tetrahydrophthalic anhydride
• Hexahydrophthalic anhydride
• Tetramethylammonium hydroxide pentahydrate
• Isatoic Anhydride
• Poly(methylhydrosiloxane)
• Trifluoromethanesulfonic anhydride
• Glutaric anhydride
• Phthalic anhydride
• cis-1,2,3,6-Tetrahydrophthalic anhydride
• Methyl
• Methylhexahydrophthalic anhydride
• Acetic anhydride
• Bicyclo[2.2.2]oct-7-ene-2,3,5,6-tetracarboxylic acid dianhydride
• HEXAHYDRO-3-METHYLPHTHALIC ANHYDRIDE,HEXAHYDRO-3-METHYLPHTHALIC ANHYDRIDE
• 3-Methylphthalic anhydride