4R,6R-Dorzolamide Chemical Properties

Melting point:

283-285 °C

Boiling point:

575.8±60.0 °C(Predicted)

Density 

1.53±0.1 g/cm3(Predicted)

storage temp. 

Refrigerator

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

9.48±0.60(Predicted)

color 

White to Off-White

Major Application

pharmaceutical (small molecule)

InChI

1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m1/s1

InChIKey

IAVUPMFITXYVAF-HTRCEHHLSA-N

SMILES

CCN[C@@H]1C[C@@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

Safety Information

WGK Germany 

WGK 3

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral

4R,6R-Dorzolamide Usage And Synthesis

Uses

ent-Dorzolamide (Dorzolamide EP Impurity A) is an enantiomer of Dorzolamide (D535100), an carbonic anhydrase inhibitor and antiglaucoma agent.

Uses

ent-Dorzolamide is an enantiomer of Dorzolamide (D535100), an carbonic anhydrase inhibitor and antiglaucoma agent.

4R,6R-Dorzolamide(120279-95-0)Related Product Information

• 2-METHYLSULFONYLTHIOPHENE
• 4R,6R-Dorzolamide
• Dorzolamide
• trans-6-Methyl-4-ethylamino-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide