1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE
1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE Basic information
- Product Name:
- 1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE
- Synonyms:
-
- BOC-FLT
- 3-N-BOC-5'-O-DIMETHOXYTRITYL-3'-O-NOSYL-THYMIDINE
- 3-N-BOC-1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-E-D-LYXOFURANOSYL]THYMIDINE
- 1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE
- 1(2H)-Pyrimidinecarboxylic acid, 3-[2-deoxy-3-O-[(4-nitrophenyl)sulfonyl]-5-O-(triphenylmethyl)-beta-D-threo-pentofuranosyl]-3,6-dihydro-5-methyl-2,6-dioxo-, 1,1-dimethylethyl ester
- 1-(2'-Deoxy-3'-O-(4-nitrobenzenesulfonyl)-5'-O-(4,4'-dimethoxytrityl)- beta-D-threo-pentafuranosyl)-3-(tert-butyloxycarbonyl)thymine
- 3-N-Boc-5'-O-dimethoxytrityl-3'-O-nosyl-thymidine 3-N-Boc-1-[5-O-(4,4'-dimethoxytrityl)-3-O-nitrophenylsulfonyl-2-deoxy-beta-D-lyxofuranosyl]thymidine
- Boc-FLT-Precursor
- CAS:
- 444717-23-1
- MF:
- C42H43N3O13S
- MW:
- 829.87
- Mol File:
- 444717-23-1.mol
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1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE Chemical Properties
- Melting point:
- 105 - 122°C
- Boiling point:
- 879.8±75.0 °C(Predicted)
- Density
- 1.42±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- -3.02±0.40(Predicted)
- color
- Light Yellow to Yellow
- Stability:
- Unstable in Aqueous Solution
- CAS DataBase Reference
- 444717-23-1
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1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE Usage And Synthesis
Chemical Properties
Yellowish amorphous solid
Uses
3-N-Boc-5'-O-DMT-3'-O-nosylthymidine (CAS# 444717-23-1) is a useful research chemical compound. It is used in the radio-synthesis of 18F-labeled deoxyfluorothymidine as radiopharmaceutical for PET by fluorination via nucleophilic substitution of precursor.
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1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE(444717-23-1)Related Product Information
- 1,3-BIS(METHOXYMETHYL)UREA
- 1-[5-(O-DIMETHOXYTRITYL)-2-DEOXY-BETA-D-THREO-PENTOFURANOSYL]THYMINE
- 1-[5-O-(4,4'-DIMETHOXYTRITYL)-3-O-NITROPHENYLSULFONYL-2-DEOXY-BETA-D-LYXOFURANOSYL]THYMINE
- 5'-O-TRITYL-2'-DEOXY-BETA-D-LYXOFURANOSYLTHYMINE
- 1-(2'-DEOXY-3'-O-(4-NITROBENZENESULFONYL)-5'-O-(4,4'-DIMETHOXYTRITYL)-BETA-D-THREO-PENTAFURANOSYL)-3-(TERT-BUTYLOXYCARBONYL)THYMINE