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2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE

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2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE Basic information

Product Name:
2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE
Synonyms:
  • N20C HYDROCHLORIDE
  • 2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE
  • N-(3,3-Diphenylpropyl)glycinamide HCl
  • Acetamide,2-[(3,3-diphenylpropyl)amino]-
  • 2-((3,3-Diphenylpropyl)amino)acetamide
CAS:
76991-05-4
MF:
C17H20N2O
MW:
268.35
Mol File:
76991-05-4.mol
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2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE Chemical Properties

storage temp. 
−20°C
solubility 
DMSO: 26 mg/mL, soluble
form 
solid
color 
white
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
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2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE Usage And Synthesis

Uses

N20C is a non-competitive NMDA receptor open-channel blocker.

Definition

ChEBI: 2-(3,3-diphenylpropylamino)acetamide is a diarylmethane.

Biological Activity

Selective, non-competitive NMDA receptor antagonist (IC 50 = 5 μ M); binds to the receptor-associated ion channel and prevents glutamate-induced Ca 2+ influx. In vivo, displays neuroprotective activity and is reported to be brain-penetrant.

2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDESupplier

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