Basic information Safety Supplier Related

10'-desmethoxystreptonigrin

Basic information Safety Supplier Related

10'-desmethoxystreptonigrin Basic information

Product Name:
10'-desmethoxystreptonigrin
Synonyms:
  • 10'-desmethoxystreptonigrin
  • DesMethoxystreptonigrin, 10'-
  • 2-Pyridinecarboxylic acid, 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolinyl)-4-(2-hydroxy-3-methoxyphenyl)-3-methyl-
  • -Desmethoxystreptonigrin
CAS:
136803-89-9
MF:
C24H20N4O7
MW:
476.443
Mol File:
136803-89-9.mol
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10'-desmethoxystreptonigrin Chemical Properties

storage temp. 
Store at -20°C
solubility 
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
A solid
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10'-desmethoxystreptonigrin Usage And Synthesis

Uses

10'-Desmethoxystreptonigrin is a close analogue of streptonigrin, produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumour activity.

Uses

10'-Desmethoxystreptonigrin is a close analogue of streptonigrin produced by selected Streptomyces species. It is a moderately potent inhibitor of farnesylation of RAS P21 protein, 3-fold more active than streptonigrin. 10'-Desmethoxystreptonigrin has also been reported to have potent and broad spectrum antibacterial and antitumor activity.

Uses

10’-Desmethoxystreptonigrin is a potent inhibitor of farnesylation of RAS P21 protein.

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