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enmein

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enmein Basic information

Product Name:
enmein
Synonyms:
  • enmein
  • Isodonin
CAS:
3776-39-4
MF:
C20H26O6
MW:
362.42
Mol File:
3776-39-4.mol
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enmein Chemical Properties

Melting point:
274-276℃ (Decomposition) (ethanol )
Boiling point:
610.3±55.0 °C(Predicted)
Density 
1.37±0.1 g/cm3(Predicted)
pka
12.66±0.60(Predicted)
form 
Solid
color 
White to off-white
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enmein Usage And Synthesis

Chemical Properties

White needle-shaped crystals, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Xihuangcao.

Uses

Enmein is isolated from I. serra with immunosuppressive effect[1].

Definition

ChEBI: A natural product found in Isodon eriocalyx.

in vivo

Enmein (inject to ear; 6.52-13.04 mg/kg; 5 days) inhibits the xylene-induced ear swelling and inhibits IL-2 expression[1].

Animal Model:Balb/c mice[1]
Dosage:6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg
Administration:Injected to ear; 6.52 mg/kg, 9.78 mg/kg or 13.04 mg/kg; 5 days
Result:Had inhibitory effect on IL-2 release in blood.

References

[1] Zhang Y, et al. Distinct immunosuppressive effect by Isodon serra extracts. Int Immunopharmacol. 2005 Dec;5(13-14):1957-65. Epub 2005 Jul 13. DOI:10.1016/j.intimp.2005.06.016
[2] Jiang B, et al. Cytotoxic ent-kaurane diterpenoids from Isodon sculponeata. Planta Med. 2002 Oct;68(10):921-5. DOI:10.1055/s-2002-34921

enmeinSupplier

BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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y.liu@mail.biobiopha.com
Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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tauto@tautobiotech.com
Chengdu Herbpurify Co.Ltd.
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2355253622; 18981954830
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2355253622@qq.com;
Sichuan Wei Keqi Biological Technology Co., Ltd.
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028-81700200 18116577057
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3003855609@qq.com
Wuxi Zhongkun Biochemical Technology Co., Ltd.
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0510-85629785 18013409632
Email
sales@reading-chemicals.com
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