EPSILON-AMANITIN
EPSILON-AMANITIN Basic information
- Product Name:
- EPSILON-AMANITIN
- Synonyms:
-
- EPSILON-AMANITIN
- Cyclo[L-Asp-L-t4Hyp-[(4S)-4-hydroxy-L-Ile-]-6-hydroxy-L-Trp2(1)-Gly-3-methyl-L-Nva-Gly-3-oxomercapto(1)-L-Ala-]
- α-Amanitin, 1-L-aspartic acid-3-[(4S)-4-hydroxy-L-isoleucine]-
- CAS:
- 21705-02-2
- MF:
- C39H53N9O14S
- MW:
- 903.96
- Mol File:
- 21705-02-2.mol
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EPSILON-AMANITIN Chemical Properties
- Density
- 1.1627 (rough estimate)
- refractive index
- 1.7400 (estimate)
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EPSILON-AMANITIN Usage And Synthesis
Uses
ε-Amanitin, a cyclic peptide isolated from a variety of mushroom species, potently binds to and inhibits the activity of RNA polymerase II[1][2].
IC 50
Traditional Cytotoxic Agents
References
[1] Jan Grunewald, et al. Amatoxin derivatives and conjugates thereof as inhibitors of rna polymerase. WO2016071856A1.
[2] Kaya E, et al. Amanitin and phallotoxin concentration in Amanita phalloides var. alba mushroom. Toxicon. 2013;76:225-233. DOI:10.1016/j.toxicon.2013.10.008
EPSILON-AMANITINSupplier
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 18892239720
- psaitong@jm-bio.com
Beijing Jin Ming Biotechnology Co., Ltd.
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
Biosynth Biological Technology (Suzhou) Co Ltd
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- 51288865780
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