2,5-DIBROMOBENZOTRIFLUORIDE Chemical Properties

Melting point:

49-51 °C(lit.)

Boiling point:

47 °C

refractive index 

1.52

Flash point:

>230 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

soluble in Methanol

form 

powder to lump

color 

White to Light yellow

BRN 

2261093

CAS DataBase Reference

7657-09-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39

RIDADR 

3276

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2903998090

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

2,5-DIBROMOBENZOTRIFLUORIDE Usage And Synthesis

Uses

2,5-Dibromobenzotrifluoride (CAS# 7657-09-2) can be used to prepare for use as anti-cancer agents. It can also be used as a novel anhydride compound to prepare polyamic acid and polyimide.

Uses

2,5-Dibromobenzotrifluoride (1,4-Dibromo-2-(trifluoromethyl)benzene) may be used to synthesize 4-bromo-2-(trifluoromethyl)benzaldehyde and functionalized alkynyl-substituted (trifluoromethyl)benzenes.

General Description

2,5-Dibromobenzotrifluoride is a halogenated hydrocarbon.

Synthesis

The general procedure for synthesizing 2,5-dibromotrifluorobenzene from 5-amino-2-bromobenzotrifluoride was as follows: first, a diazonium salt solution was prepared according to the method described in Example 3. Subsequently, the cooled diazonium salt solution was rapidly poured into a pre-cooled and well-stirred mixture of CuBr (13 g, 0.091 mol) and concentrated hydrobromic acid (71 g, 0.44 mol). The reaction mixture was slowly warmed to room temperature and stirred continuously for 2 to 3 hours. Finally, the reaction system was heated to 60-70 °C and the target product 2,5-dibromotrifluorobenzene was obtained upon completion of the reaction. The yield was 63%.

References

[1] Patent: WO2016/63300, 2016, A1. Location in patent: Page/Page column 9

2,5-DIBROMOBENZOTRIFLUORIDE(7657-09-2)Related Product Information

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