Oxyresveratrol
Oxyresveratrol Basic information
- Product Name:
- Oxyresveratrol
- Synonyms:
-
- 4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol
- 4-[(E)-2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,3-diol
- Oxyresveratrol ,4-[(E)-2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,3-diol
- Oxyresveratrol
- 1G/25G/1KG
- 2,3',4,5'-Tetrahydroxy-trans-stilbene
- 25g
- (E)-4-(3,5-dihydroxystyryl)benzene-1,3-diol
- CAS:
- 29700-22-9
- MF:
- C14H12O4
- MW:
- 244.24
- EINECS:
- 608-401-8
- Product Categories:
-
- API
- reagent
- APIs
- standard substance
- 29700-22-9
- Mol File:
- 29700-22-9.mol
Oxyresveratrol Chemical Properties
- Melting point:
- 201-202.5 °C
- Boiling point:
- 523.8±30.0 °C(Predicted)
- Density
- 1.468±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Ethyl Acetate (Slightly), Methanol
- pka
- 9.14±0.10(Predicted)
- form
- Solid
- color
- Pale Yellow to Pale Beige
- InChIKey
- PDHAOJSHSJQANO-OWOJBTEDSA-N
- CAS DataBase Reference
- 29700-22-9(CAS DataBase Reference)
Oxyresveratrol Usage And Synthesis
Description
Oxyresveratrol is an effective tyrosinase inhibitor, and has anti-tussive and anti-asthmatic, antioxidant, anti-inflammatory and analgesic effects.
Chemical Properties
White powder
Uses
Oxyresveratrol is a natural hydroxystilbene with similar bioactivity to resveratrol. COX-1 inhibitor like resveratrol (R150000), anti-cancer agent.
Definition
ChEBI: Oxyresveratrol is a stilbenoid.
Biological Activity
Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM)
In vitro:
1)oxyresveratrol exhibited more than 50% inhibition at 100 μM on L-tyrosine oxidation by murine tyrosinase activity.
2) oxyresveratrol showed an IC50 value of 52.7 μM on the enzyme activity.
3) oxyresveratrol works through reversible inhibition of tyrosinase activity rather than suppression of the expression and synthesis of the enzyme.
In vivo:
1) Oxyresveratrol (10 or 20 mg/kg) significantly reduced the brain infarct volume by approximately 54% and 63%, respectively, when compared to vehicle-treated MCAO rats.
2) oxyresveratrol treatment diminished cytochrome c release and decreasedcaspase-3 activation in MCAO rats.
Solubility in organics
Oxyresveratrol is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of oxyresveratrol in these solvents is approximately 50 mg/ml.
OxyresveratrolSupplier
- Tel
- 021-58180488
- sales@Medchemleader.com
- Tel
- 029-86107037-8019 15332321378
- sales@pioneerbiotech.com
- Tel
- 0571-28313180 17767135330
- info@great-forest.com
- Tel
- 13259841664
- xaxlbio@vip.163.com
- Tel
- sales@boylechem.com
Oxyresveratrol(29700-22-9)Related Product Information
- 3,4',5-TRIMETHOXY-TRANS-STILBENE
- Rhapontigenin 3'-O-glucoside
- TRANS-RESVERATROL 4'-O-BETA-D-GLUCURONIDE
- oxypaeoniflora
- Ammothamnine
- Zinc hydroxide
- Glabridin
- Polydatin
- Tetrahydroberberine
- 1,10-Phenanthroline hydrate
- Resveratrol
- Fingolimod hydrochloride
- SINOMENINE HYDROCHLORIDE
- OXYPEUCEDANIN
- oxysophoridine
- 3'-Hydroxypterostilbene
- rhapontigenin
- (E)-3-Hydroxy-4',5-dimethoxystilbene