Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  Biochemical Engineering >  Plant extracts >  Oxyresveratrol

Oxyresveratrol

Basic information Safety Supplier Related

Oxyresveratrol Basic information

Product Name:
Oxyresveratrol
Synonyms:
  • 4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,3-diol
  • 4-[(E)-2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,3-diol
  • Oxyresveratrol ,4-[(E)-2-(3,5-Dihydroxyphenyl)ethenyl]benzene-1,3-diol
  • Oxyresveratrol
  • 1G/25G/1KG
  • 2,3',4,5'-Tetrahydroxy-trans-stilbene
  • 25g
  • (E)-4-(3,5-dihydroxystyryl)benzene-1,3-diol
CAS:
29700-22-9
MF:
C14H12O4
MW:
244.24
EINECS:
608-401-8
Product Categories:
  • API
  • reagent
  • APIs
  • standard substance
  • 29700-22-9
Mol File:
29700-22-9.mol
More
Less

Oxyresveratrol Chemical Properties

Melting point:
201-202.5 °C
Boiling point:
523.8±30.0 °C(Predicted)
Density 
1.468±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Ethyl Acetate (Slightly), Methanol
pka
9.14±0.10(Predicted)
form 
Solid
color 
Pale Yellow to Pale Beige
InChIKey
PDHAOJSHSJQANO-OWOJBTEDSA-N
CAS DataBase Reference
29700-22-9(CAS DataBase Reference)
More
Less

Safety Information

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26-24/25
WGK Germany 
3
HS Code 
29072990
More
Less

Oxyresveratrol Usage And Synthesis

Description

Oxyresveratrol is an effective tyrosinase inhibitor, and has anti-tussive and anti-asthmatic, antioxidant, anti-inflammatory and analgesic effects.

Chemical Properties

White powder

Uses

Oxyresveratrol is a natural hydroxystilbene with similar bioactivity to resveratrol. COX-1 inhibitor like resveratrol (R150000), anti-cancer agent.

Definition

ChEBI: Oxyresveratrol is a stilbenoid.

Biological Activity

Oxyresveratrol is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. It effectively scavenges H2O2, NO (IC50 = 45.3 μM), and the artificial free radical 2,2-diphenyl-l-picrylhydrazyl (IC50 = 28.9 μM)
In vitro:
1)oxyresveratrol exhibited more than 50% inhibition at 100 μM on L-tyrosine oxidation by murine tyrosinase activity.
2) oxyresveratrol showed an IC50 value of 52.7 μM on the enzyme activity.
3) oxyresveratrol works through reversible inhibition of tyrosinase activity rather than suppression of the expression and synthesis of the enzyme.
In vivo:
1) Oxyresveratrol (10 or 20 mg/kg) significantly reduced the brain infarct volume by approximately 54% and 63%, respectively, when compared to vehicle-treated MCAO rats.
2) oxyresveratrol treatment diminished cytochrome c release and decreasedcaspase-3 activation in MCAO rats.

Solubility in organics

Oxyresveratrol is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide, which should be purged with an inert gas. The solubility of oxyresveratrol in these solvents is approximately 50 mg/ml.

OxyresveratrolSupplier

Chemleader Biomedical Co., Limited. Gold
Tel
021-58180488
Email
sales@Medchemleader.com
Shaanxi Pioneer Biotech CO., Ltd Gold
Tel
029-86107037-8019 15332321378
Email
sales@pioneerbiotech.com
Hangzhou Great Forest Biomedical Ltd. Gold
Tel
0571-28313180 17767135330
Email
info@great-forest.com
Xi 'an Xinlu Biological Technology Co. LTD Gold
Tel
13259841664
Email
xaxlbio@vip.163.com
Shanghai Boyle Chemical Co., Ltd.
Tel
Email
sales@boylechem.com