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ChemicalBook >  Product Catalog >  Pharmaceutical intermediates >  Bulk Drug Intermediates >  (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate

(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate

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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Basic information

Product Name:
(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
Synonyms:
  • (1R)-(S)-PINANEDIOL 1-AMMONIUM TRIFLUOROACETATE-3-METHYLBUTANE-1-BORONATE
  • (R)-BoroLeu-(+)-Pinanediol-CF3COOH
  • (R)-BoroLeu-(+)-Pinanediol-CF3CO2H
  • (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate
  • (αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetate
  • Bortezomib Intermediate 1
  • (R)-BoroLeu-(+)-Pinanediol trifluoroacetate
  • (αR,3aS,4S,6S,7aR)-
CAS:
179324-87-9
MF:
C17H29BF3NO4
MW:
379.23
EINECS:
2017-001-1
Product Categories:
  • Amines
  • Boron Derivatives
  • Chiral Reagents
  • Intermediates
Mol File:
179324-87-9.mol
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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Chemical Properties

Melting point:
157-159°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Ethanol (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1/C15H28BNO2.C2HF3O2/c1-9(2)6-13(17)16-18-12-8-10-7-11(14(10,3)4)15(12,5)19-16;3-2(4,5)1(6)7/h9-13H,6-8,17H2,1-5H3;(H,6,7)/t10-,11-,12+,13-,15-;/s3
InChIKey
SRFQKJZNJYTMNI-XXOUUVOINA-N
SMILES
C(F)(F)(F)C(=O)O.C[C@@]12OB([C@@H](N)CC(C)C)O[C@]1([H])C[C@]1([H])C[C@@]2([H])C1(C)C |&1:8,11,18,21,24,r|
CAS DataBase Reference
179324-87-9(CAS DataBase Reference)
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Safety Information

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
29209090
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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate Usage And Synthesis

Chemical Properties

White Solid

Uses

Bortezomib intermediate

Uses

Bortezomib (B675700) intermediate. A boronic acid dipeptide derivative as proteasome inhibitors.

(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetateSupplier

Jiangsu Vcare PharmaTech Co., Ltd. Gold
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Shanghai Zhuorui Chemical Co.,Ltd. Gold
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Shandong Platinum Pharmaceutical Co., Ltd. Gold
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(aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate(179324-87-9)Related Product Information