Bombesin Chemical Properties

Density 

1.50±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

solubility 

0.05 M acetic acid: 20 mg/mL, clear, colorless

pka

13.04±0.46(Predicted)

form 

Powder

color 

White to off-white

optical activity

-20.624〔DMF-HMPT(8：2)〕

Merck 

13,1320

BRN 

9611365

Sequence

Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

BD3480000

F 

10

MSDS

• Language:English Provider:SigmaAldrich

Bombesin Usage And Synthesis

Uses

Gut tetradecapeptide with the ability to stimulate release of various hormones

Purification Methods

Purify Bombesin by gel filtration on a small column of Sephadex G-10 and elute with 0.01 M AcOH. This procedure removes lower molecular weight contaminants which are retarded on the column. The procedure should be repeated twice, and the material should now be homogeneous on electrophoresis, and on chromatography it gives a single active spot which is negative to ninhydrin but positive to Cl2 and iodoplatinate reagents. RF on paper chromatography (n-BuOH/pyridine/AcOH/H2O :: 37.5: 25:7.5:30) is 0.55 for Bombesin and 0.65 for Alytin. [Bernardi et al. Experientia Part 1 27 166 1971, Anastasi et al. Part 2 27 873 1971.] The hydrochloride has m 185o(dec) (from EtOH) [] D -20.6o [c 0.65, Me2NCHO/(Me2N)3PO (8:2)]. [For the stimulation of inositol phosphate see Lloyd et al. Biochem J 260 813 1989.]

Bombesin(31362-50-2)Related Product Information

• Chloral hydrate
• Cellulose acetate
• L-Glutamine
• Benzyl acetate
• Vinyl acetate
• Ethyl acetate
• D-(-)-Asparagine monohydrate
• Sodium acetate
• Butyl acetate
• MAGAININ I
• BA 1
• DELTORPHIN
• bombesin fragment 8-14
• ACETATE
• L-Asparagine
• Bombesin
• Gastrin（Bombesin)
• hydrate