3-Trifluoromethoxyphenylboronic acid Chemical Properties

Melting point:

84-89 °C (lit.)

Boiling point:

266.6±50.0 °C(Predicted)

Density 

1.41±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

7.39±0.10(Predicted)

form 

Powder and Chunks

color 

Almost white to slightly beige

BRN 

7531456

CAS DataBase Reference

179113-90-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

37/39-26-36

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

3-Trifluoromethoxyphenylboronic acid Usage And Synthesis

Chemical Properties

almost white to slightly beige powder and chunk

Uses

suzuki reaction

Uses

3-(Trifluoromethyloxy)phenylboronic Acid is used as a reagent in the preparation of pyrrolo[1,2-a]pyrazinones as inhibitors of PIM kinases.

Uses

Precursor commonly used in the synthesis of biologically active compounds including:

• Multisubstituted purines for use as P2X7 antagonists in the treatment of pain
• Heteroaryl substituted tetrahydropyrroloijquinolinone derivatives as aldosterone synthase inhibitors
• Fluorohydroquinolineethanol as a CETP inhibitor
• Biaryl amides with muscarinic acetylcholine receptor subtype M1 agonist activity
• C2-aryl pyrrolobenzodiasepine antitumor agents
• Piperazine-bisamide for obesity treatments

3-Trifluoromethoxyphenylboronic acid(179113-90-7)Related Product Information

• p-Trifluoromethoxy phenol
• Stearic acid
• 4-Trifluoromethylphenylboronic acid
• 4-Methoxybenzyl alcohol
• 4-(Trifluoromethoxy)benzaldehyde
• 2-(Trifluoromethoxy)aniline
• Anisole
• p-Anisaldehyde
• 4-Methoxybenzoyl chloride
• Ethyl 2-(Chlorosulfonyl)acetate
• 4-(Trifluoromethoxy)chlorobenzene
• 2,3,4-Trimethoxybenzaldehyde
• 4'-(Trifluoromethoxy)acetophenone
• Citric acid
• Phenylboronic acid
• (4-METHOXYPHENYL)-BORANE
• (Trifluoromethoxy)benzene
• 3-Methoxyacetophenone