METHYL CAFFEATE Chemical Properties

Melting point:

158-161°C

Boiling point:

368℃

Density 

1.318

refractive index 

1.5168 (estimate)

Flash point:

80 °C

storage temp. 

Sealed in dry,2-8°C

solubility 

Acetonitrile (Slightly), Dimethylformamide, DMSO, Ethyl Acetate, Methanol (Slightly)

form 

Solid

pka

8.71±0.18(Predicted)

color 

Off-White to Brown

λmax

328nm(MeOH)(lit.)

Stability:

Light Sensitive

LogP

1.190 (est)

CAS DataBase Reference

3843-74-1(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

HS Code 

2918.29.7500

MSDS

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METHYL CAFFEATE Usage And Synthesis

Description

Caffeic acid methyl ester is an ester of a naturally occurring phenolic compound found in P. amplexicaule var. sinense and S. torvum fruits. At 40 mg/kg, it demonstrates antihyperglycemic and antidiabetic activity in diabetic rats, upregulating GLUT4 and regenerating pancreatic β-cells. At 10 mg/kg, it can induce anti-inflammatory and antinociceptive effects in rat models of edema and pain, inhibiting nitric oxide and prostaglandin E₂ production, as well as tumor necrosis factor-α release.

Chemical Properties

slightly yellowish solid

Uses

Inhibitor of protein tyrosine kinase

Definition

ChEBI: An alkyl caffeate ester formed by the formal condensation of caffeic acid with methyl alcohol.

METHYL CAFFEATE(3843-74-1)Related Product Information

• ETHYL CAFFEATE
• Phenethyl caffeate
• Chlorogenic acid
• RESCINNAMINE
• 3,4,5-TRIMETHOXYCINNAMIC ACID ETHYL ESTER
• Ethyl 4-hydroxy-3-methoxycinnamate
• ECHINACOSIDE
• (E)-3-(4-hydroxy-3-methoxy-phenyl)acrylic acid methyl este
• CYNARIN
• Caffeic acid
• Rosmarinic acid
• ISOBUTYL ALPHA-CYANO-3,4-METHYLENEDIOXYCINNAMATE
• 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE
• METHYL (E)-3-(1,3-BENZODIOXOL-5-YL)-2-PROPENOATE
• ETHYL 3-(2-CHLORO-3,4-DIMETHOXYPHENYL)ACRYLATE
• Cyclohexanecarboxylic acid, 3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-, monopotassium salt, [1S-(1alpha,3beta,4alpha,5alpha)]-, compd. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione (1:1)
• ETHYL 3-(1,3-BENZODIOXOL-5-YL)-2-CYANOACRYLATE
• AKOS BBS-00008191