Basic information Description References Safety Supplier Related
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2,5-Dimethylphenol

Basic information Description References Safety Supplier Related

2,5-Dimethylphenol Basic information

Product Name:
2,5-Dimethylphenol
Synonyms:
  • XYLENOL(2,5-)
  • 1,2,5-Xylenol
  • 1,4-Dimethyl-2-hydroxybenzene
  • 1-Hydroxy-2,5-dimethylbenzene
  • 2,5-dimethyl-pheno
  • 2,5-XYLENOL
  • 2,5-DIMETHYLPHENOL
  • 2,5-DMP
CAS:
95-87-4
MF:
C8H10O
MW:
122.16
EINECS:
202-461-5
Product Categories:
  • Antioxidant
  • INTERMEDIATESOFGEMFIBROIL
  • Aromatic Phenols
Mol File:
95-87-4.mol
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2,5-Dimethylphenol Chemical Properties

Melting point:
75-77 °C
Boiling point:
212 °C(lit.)
Density 
0.971 g/mL at 25 °C(lit.)
vapor pressure 
0.208 hPa (25 °C)
FEMA 
3595 | 2,5-XYLENOL
refractive index 
1.5120
Flash point:
85 °C
storage temp. 
Store below +30°C.
solubility 
3.54g/l slightly soluble
form 
Crystals
pka
pK1:10.22 (25°C)
color 
slightly brown
Odor
at 0.10 % in propylene glycol. sweet naphthyl phenolic smoke bacon
Odor Type
phenolic
explosive limit
1.4%(V)
Water Solubility 
1 g/100 mL (60 ºC)
Merck 
14,10082
JECFA Number
706
BRN 
1099260
Exposure limits
ACGIH: TWA 1 ppm
InChIKey
NKTOLZVEWDHZMU-UHFFFAOYSA-N
LogP
2.34-2.6 at 25℃
CAS DataBase Reference
95-87-4(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2,5-dimethyl-(95-87-4)
EPA Substance Registry System
2,5-Dimethylphenol (95-87-4)
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Safety Information

Hazard Codes 
T,N
Risk Statements 
24/25-34-51/53
Safety Statements 
26-36/37/39-45-61
RIDADR 
UN 2261 6.1/PG 2
WGK Germany 
3
RTECS 
ZE5775000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29071400
Hazardous Substances Data
95-87-4(Hazardous Substances Data)

MSDS

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2,5-Dimethylphenol Usage And Synthesis

Description

2, 5-dimethylphenol (also known as 2, 5-xylenol, or p-xylenol, chemical formula: (CH3)2C6H3OH.) is a chemical compound as one of the six isomers of xylenol. It is found in alcoholic beverages, coffee and whisky. It is a kind of flavoring agent belonging to the family of Ortho Cresols. One of its applications is for the synthesis of Mexilethine. It has important industrial importance, e.g. for the manufacture of antioxidants. It is also a monomer for the poly (p-phenylene oxide) engineering resins through carbon-oxygen oxidative coupling. It is traditionally extracted from the coal tar.

References

https://en.wikipedia.org/wiki/2,6-Xylenol
https://en.wikipedia.org/wiki/Xylenol
https://pubchem.ncbi.nlm.nih.gov/compound/2_5-dimethylphenol#section=Top

Chemical Properties

WHITE TO CREAM COLORED CRYSTALS

Chemical Properties

2,5-Xylenol has a creosote, sweet, medicinal taste.

Occurrence

Reported found in coffee, smoked fatty fish, processed lean fish, malt whiskey, Scotch blended whiskey, katsuobushi (dried bonito) and kumazasa (Sasa albo-marginata).

Uses

Used to make phenolic resins and (in isomeric mixtures) as an antioxidant for lubricating oils, gasoline, and elastomers. Also used as perfuming agents.

Definition

ChEBI: 2,5-xylenol is a member of the class of phenols that phenol substituted by methyl groups at positions 2 and 5. It has a role as a volatile oil component and an animal metabolite. It derives from a hydride of a p-xylene.

Aroma threshold values

Detection: 400 ppb

Taste threshold values

Taste characteristics at 10 ppm: musty, chemical, stringent and phenolic.

General Description

Colorless to off-white crystalline solid. Odor threshold concentration 0.4 mg/L. Taste threshold concentration 0.5 mg/L.

Air & Water Reactions

2,5-Dimethylphenol is hygroscopic. Insoluble in water.

Reactivity Profile

2,5-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides and oxidizing agents. 2,5-Dimethylphenol corrodes steel, brass, copper and copper alloys.

Health Hazard

Symptoms of exposure to this compound may include severe irritation and burns of the skin and eyes; irritation of the respiratory tract, dizziness, stomach pain, exhaustion, coma and damage to the liver or kidneys. Other symptoms include headache, nausea and vomiting. It may cause corrosion of the tissues of the mucous membranes and upper respiratory tract, eyes and skin. Inhalation may result in burning sensation, coughing, wheezing, laryngitis and shortness of breath. Inhalation may be fatal as a result of spasm, inflammation and edema of the larynx and bronchi; chemical pneumonitis and pulmonary edema. Symptoms of exposure to this class of compounds include skin sensitization, profuse sweating, painless blanching or erythema of the skin, intense thirst, diarrhea, cyanosis from methemoglobinemia, hyperactivity, stupor, blood pressure fall, hyperpnea, abdominal pain, hemolysis and convulsions. If death from respiratory failure is not immediate, jaundice and oliguria or anuria may occur.

Fire Hazard

Flash point data for 2,5-Dimethylphenol are not available. 2,5-Dimethylphenol is probably combustible.

Safety Profile

Poison by ingestion. Moderately toxic by an unspecified route. When heated to decomposition it emits acrid smoke and irritating fumes. Questionable carcinogen with experimental tumorigenic data. Used in disinfectants, solvents, pharmaceuticals, plasticizers, and wetting agents. See also other xylenol entries.

Purification Methods

Crystallise 2,5-xylenol from EtOH/ether. [Beilstein 6 IV 3164.]

2,5-Dimethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

2,5-DimethylphenolSupplier

Nanjing Datang Chemical Co., Ltd Gold
Tel
25-25-85431992 13951889906
Email
vip@chemdatang.com
Products Intro
Product Name:XYLENOL(2,5-);1,2,5-Xylenol;1,4-Dimethyl-2-hydroxybenzene;1-Hydroxy-2,5-dimethylbenzene;2,5-dimethyl-pheno;3,6-Dimethylphenol;3,6-Xylenol;6-Methyl-m-cresol
CAS:95-87-4
Purity:99% Package:25KG
Powerful Chemical (Shanghai) Co., Ltd. Gold
Tel
021-62211590 18917958225
Email
pwfchem@163.com
Products Intro
Product Name:2,5-dimethyl phenol
CAS:95-87-4
Purity:99% Package:25kg;1kg
Changzhou Junchi Chemical Co.,ltd. Gold
Tel
0519-85518211 15195021697
Email
85518211@chemjunchi.com
Products Intro
Product Name:2,5-Dimethylphenol
CAS:95-87-4
Purity:99% Package:50kg/桶;200 kg/桶
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Email
market03@meryer.com
Products Intro
Product Name:2,5-DiMethylphenol
CAS:95-87-4
Purity:99+% Remarks:11654
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
Products Intro
Product Name:2,5-DiMethylphenol
CAS:95-87-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g