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Boldine

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Boldine Basic information

Product Name:
Boldine
Synonyms:
  • (+)-(s)-boldine
  • (s)-boldine
  • (s)-yl
  • 1,10-dimethoxy-6a-alpha-aporphine-2,9-diol
  • 1,10-dimethoxy-6a-alpha-aporphine-9-diol
  • 4h-dibenzo(de,g)quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-meth
  • 4h-dibenzo[de,g]quinoline-2,9-diol,5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl
  • boldin
CAS:
476-70-0
MF:
C19H21NO4
MW:
327.37
EINECS:
207-509-9
Mol File:
476-70-0.mol
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Boldine Chemical Properties

Melting point:
162-164 °C
Boiling point:
465.27°C (rough estimate)
Density 
1.2223 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
2-8°C
solubility 
Acetonitrile (Slightly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
9.75±0.20(Predicted)
color 
Yellow to Dark Brown
Merck 
13,1316
BRN 
94036
LogP
0.837 (est)
CAS DataBase Reference
476-70-0(CAS DataBase Reference)
EPA Substance Registry System
4H-Dibenzo[de,g]quinoline-2,9-diol, 5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-, (6aS)- (476-70-0)
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Safety Information

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
1-20-24/25-45-36-26
RIDADR 
1544
WGK Germany 
3
RTECS 
CE0750000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29399990

MSDS

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Boldine Usage And Synthesis

Uses

antineoplastic

Uses

boldine is attributed with strong anti-oxidant properties. It has also demonstrated an ability to protect against uVB rays. Boldine is a constituent of the boldo plant (Peumus boldus Mol.) native to Chile, and is found in the plant’s leaves and bark.

Definition

ChEBI: Boldine is an aporphine alkaloid.

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