Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate Chemical Properties

storage temp. 

Inert atmosphere,Room Temperature

form 

Solid

color 

White to off-white

InChI

InChI=1S/C12H19NO3S.Na.H/c1-3-13(8-5-9-17(14,15)16)12-7-4-6-11(2)10-12;;/h4,6-7,10H,3,5,8-9H2,1-2H3,(H,14,15,16);;

InChIKey

CMQWQOXGZUZROJ-UHFFFAOYSA-N

SMILES

N(C1C=CC=C(C)C=1)(CC)CCCS(O)(=O)=O.[NaH]

CAS DataBase Reference

40567-80-4(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-37/39-24/25

WGK Germany 

3

F 

3

HS Code 

29214300

MSDS

• Language:English Provider:SigmaAldrich

Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate Usage And Synthesis

Description

N-ethyl-N-(3-sulfopropyl)-3-methylaniline sodium salt (TOPS), which is one of the new Trinder's color reagents, and the appearance is white crystalline powder. Because of its molecular structure and the sulfopropyl group on the single atom connected to the benzene ring, there is one less hydroxyl group with a slightly stronger stability, high water solubility, and high detection sensitivity. It is widely used in diagnostic and biochemical testing, mainly for the colorimetric determination of uric acid and cholesterol; when used as a water-soluble reagent, it can be used to determine hydrogen peroxide by enzymatic photometry.

Chemical Properties

White powder

Uses

TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H2O2 and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection[1].

References

[1] Zhuang QQ, et al. Peroxidase-like activity of nanocrystalline cobalt selenide and its application for uric acid detection. Int J Nanomedicine. 2017 Apr 20;12:3295-3302. DOI:10.2147/IJN.S128556

Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate(40567-80-4)Related Product Information

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