(R)-(-)-2-Amino-3-methyl-1-butanol Chemical Properties

Melting point:

35-36 °C(lit.)

Boiling point:

189-190 °C(lit.)

alpha 

-16.5 º (c=10, EtOH)

Density 

0.931 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.455

Flash point:

194 °F

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

pka

12.82±0.10(Predicted)

form 

Low Melting Crystals or Crystalline Mass

color 

White to light yellow

optical activity

[α]20/D 16°, c = 10 in ethanol

Sensitive 

Air Sensitive

BRN 

1719138

InChIKey

NWYYWIJOWOLJNR-YFKPBYRVSA-N

CAS DataBase Reference

4276-09-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37-36-36/37/38

WGK Germany 

3

F 

10-34

HS Code 

29051990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(R)-(-)-2-Amino-3-methyl-1-butanol Usage And Synthesis

Chemical Properties

white to light yellow crystal powde

Uses

D-Valinol is used as a reagent in the synthesis of the HIV type 1 integrase inhibitor Elvitegravir (E509000). D-Valinol is also used in the preparation of novel 2-(alkylmorpholin-4-yl)-6-(3-fluoropyridin-4-yl)-pyrimidin-4(3H)-ones as orally active GSK-3β inhibitors for Alzheimer''s disease.

(R)-(-)-2-Amino-3-methyl-1-butanol(4276-09-9)Related Product Information

• TRISTEARIN
• Methylparaben
• Kresoxim-methyl
• VALINOMYCIN
• Lithium bis(trimethylsilyl)amide
• Tris(hydroxymethyl)aminomethane
• Methyl acrylate
• Bensulfuron methyl
• EC 2.6.1.2
• (S)-(+)-2-Amino-1-butanol
• Thiophanate-methyl
• Acetaminophen
• tert-Butanol
• N,N-Dimethyl-1,4-phenylenediamine
• 1,3-Dimethylbarbituric acid
• 1-Butanol
• Fosfomycin tromethamine
• Ketorolac tromethamine