ChemicalBook > Product Catalog > Organic Chemistry > Carboxylic acids and derivatives > Acyclic carboxylic acid > Benzilic acid
Benzilic acid
Benzilic acid Basic information
- Product Name:
- Benzilic acid
- Synonyms:
-
- BENZILIC ACID extrapure
- Benzilic acidDiphenylglycolic acid
- TrospiuM Chloride Related CoMpound A
- Trospium Chloride Related Compound A (20 mg) (Benzilic Acid) (Internationally Restricted Sales Item)
- BENZILIC ACID FOR SYNTHESIS 1 KG
- BENZILIC ACID FOR SYNTHESIS 250 G
- Benzeneacetic acid,a-hydroxy-a-phenyl-
- Trospium Chloride Related Compound A (20 mg) (Benzilic Acid) (International Restricted Sales Item)
- CAS:
- 76-93-7
- MF:
- C14H12O3
- MW:
- 228.25
- EINECS:
- 200-993-2
- Product Categories:
-
- Pharmaceutical Intermediates
- Organics
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
- Mol File:
- 76-93-7.mol
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Benzilic acid Chemical Properties
- Melting point:
- 149-151 °C(lit.)
- Boiling point:
- 180 °C
- Density
- 1.28
- refractive index
- 1.5805 (estimate)
- Flash point:
- 180°C/22mm
- storage temp.
- Store below +30°C.
- solubility
- 1.41g/l (experimental)
- form
- Powder
- pka
- pKa (25°): 3.036
- color
- White to cream-white
- Water Solubility
- 1.41 g/L (25 ºC)
- Merck
- 14,1080
- BRN
- 521402
- Stability:
- Stable. Incompatible with strong oxidizing agents. Combustible.
- LogP
- 2.300
- CAS DataBase Reference
- 76-93-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzeneacetic acid, «alpha»-hydroxy-«alpha»-phenyl-(76-93-7)
- EPA Substance Registry System
- Benzilic acid (76-93-7)
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Safety Information
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38-20/21/22
- Safety Statements
- 36-36/37/39-26
- WGK Germany
- 3
- RTECS
- DD2064000
- TSCA
- Yes
- HS Code
- 29181980
- Hazardous Substances Data
- 76-93-7(Hazardous Substances Data)
- Toxicity
- LD50 orl-mus: 2 g/kg AIPTAK 116,154,58
MSDS
- Language:English Provider:2-Hydroxy-2,2-diphenylacetic acid
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
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Benzilic acid Usage And Synthesis
Chemical Properties
white powder
Uses
Benzilic Acid is an impurity of Trospium (T892800), a tropine derivative with anticholinergic activity and a antiispasmodic agent.
Definition
ChEBI: Benzilic acid is a 2-hydroxy monocarboxylic acid.
Synthesis Reference(s)
The Journal of Organic Chemistry, 29, p. 1631, 1964 DOI: 10.1021/jo01029a509
Safety Profile
Moderately toxic by subcutaneousroute. Slightly toxic by ingestion. When heated todecomposition it emits acrid smoke and irritating vapors.
Purification Methods
Crystallise benzilic acid from *benzene (ca 6mL/g), or hot H2O. [Beilstein 10 IV 1256.]
Benzilic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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Benzilic acid(76-93-7)Related Product Information
- Glycolic acid
- Stearic acid
- POLY(2-HYDROXYACETIC ACID)
- 1,5-Diphenylcarbazide
- Ethyl glycolate
- Citric acid
- CHLOROPHOSPHONAZO III
- Chlorodiphenylphosphine
- 2,2-Diphenylacetic acid
- Bis(2-ethylhexyl) phthalate
- Dichlorodiphenylsilane
- Sodium glycolate
- 3,4-Dihydroxyphenylacetic acid
- Potassium hydrogen phthalate
- 2-Hydroxyphenylacetic acid
- Diphenyl ether
- 1,3-Diphenyl-2-thiourea
- m-Phenylenediamine