(S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE Chemical Properties

Melting point:

82-86 °C (lit.)

Boiling point:

305.7±31.0 °C(Predicted)

Density 

1.172±0.06 g/cm3(Predicted)

pka

15.50±0.20(Predicted)

optical activity

[α]20/D 75°, c = 1 in H2O

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

(S)-(-)-TETRAHYDROFURAN-2-CARBOXYLIC ACID AMIDE Usage And Synthesis

Uses

(S)-(?)-Tetrahydrofuran-2-carboxamide can be used as a precursor for the preparation of (S)-tetrahydrofuran-2-carbonitrile (THFCN) via dehydration reaction using thionyl chloride and DMF. THFCN can be further methylated with methylmagnesium chloride (Grignard reagent) to produce (S)-1-(tetrahydrofuran-2-yl)ethenone.

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