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Ac-rC Phosphoramidite

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Ac-rC Phosphoramidite Basic information

Product Name:
Ac-rC Phosphoramidite
Synonyms:
  • N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite
  • (2S,3S,4S,5S)-5-(4-AcetaMido-2-oxopyriMidin-1(2H)-yl)-2-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-((tert-butyldiMethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoraMidite
  • 5'-O-(4,4'-DiMethoxytrityl)-N4-acetyl-2'-O-t-butyldiMethylsilylcytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoraMidite
  • 5'-O-DMTr-N4-Ac-2'-O-TBDMS-cytidine-3'-CED PhosphoraMidite
  • DMT-2′O-TBDMS-rC(ac) Phosphoramidite
  • 2'-TBDMS -Ac-rC-CE-Phosphoramidite
  • 5'-DMT-2'-O-TBDMS- N4-Acetyl-Cytidine Phosphoramidite
  • 5'-O-DMT-2'-O-tert-butyldimethylsilyl-N4-Acetyl-cytidine 3'-CE phosphoramidite
CAS:
121058-88-6
MF:
C47H64N5O9PSi
MW:
902.11
EINECS:
2017-001-1
Product Categories:
  • Pharmaceutical
  • Amidite
Mol File:
121058-88-6.mol
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Ac-rC Phosphoramidite Chemical Properties

storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO: 100 mg/mL (110.85 mM)
form 
powder
pka
10.16±0.20(Predicted)
color 
white to off-white
InChI
InChI=1/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/s3
InChIKey
QKWKXYVKGFKODW-UMIUEWJMNA-N
SMILES
C(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=CC(NC(=O)C)=NC2=O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,39,48,r|
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Safety Information

WGK Germany 
3
HS Code 
29349990
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Ac-rC Phosphoramidite Usage And Synthesis

Uses

DMT-2′O-TBDMS-rC(ac) Phosphoramidite was used for inverse electron-demand Diels-Alder reactions for selective and efficient labeling of RNA.

Application

Ac-rC Phosphoramidite (DMT-2′O-TBDMS-rC(ac) Phosphoramidite) is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).

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