GUANYLYL-5'-IMIDODIPHOSPHATE, TETRALITHIUM SALT Chemical Properties

storage temp. 

-20°C

solubility 

PBS (pH 7.2): 10 mg/ml

form 

A crystalline solid

color 

White to off-white

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

GUANYLYL-5'-IMIDODIPHOSPHATE, TETRALITHIUM SALT Usage And Synthesis

Uses

Guanylyl imidodiphosphate (Gpp(NH)p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity[1][2].

References

[1] B J Terry, et al. Assembly and disassembly properties of microtubules formed in the presence of GTP, 5'-guanylyl imidodiphosphate, and 5'-guanylyl methylenediphosphate. J Biol Chem. 1980 Nov 10;255(21):10532-6. PMID:6253478
[2] H Abou-Issa, et al. Modulation of follicle-stimulating hormone-sensitive rat testicular adenylate cyclase activity by guanyl nucleotides. Endocrinology. 1979 Jan;104(1):189-93. DOI:10.1210/endo-104-1-189

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