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2-Chloro-3-hydroxypyridine

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2-Chloro-3-hydroxypyridine Basic information

Product Name:
2-Chloro-3-hydroxypyridine
Synonyms:
  • 2-Chloro-3-hydroxypyridine≥ 99% (HPLC)
  • 2-CHLORO-PYRIDINE-3-OL
  • 2-CHLOROPYRIDIN-3-OL
  • 2-CHLORO-3-HYDROXYPYRIDINE
  • 2-CHLORO-3-PYRIDINOL
  • 2-CHLORO-3-HYDROXYPYRIDINE 2-CHLORO-PYRIDIN-3-OL
  • 2-CHLORO-3-HYDROXYPYRIDINE (2-CHLORO-3-PYRIDINOL)
  • 2-chloro-3-pyridino
CAS:
6636-78-8
MF:
C5H4ClNO
MW:
129.54
EINECS:
229-635-3
Product Categories:
  • Chloropyridines
  • Halopyridines
  • PYRIDINE
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Halides
  • Pyridines
  • Pyridines derivatives
  • Imidazoles
Mol File:
6636-78-8.mol
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2-Chloro-3-hydroxypyridine Chemical Properties

Melting point:
170-172 °C (lit.)
Boiling point:
316.2±22.0 °C(Predicted)
Density 
1.2309 (rough estimate)
refractive index 
1.4510 (estimate)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
4.32±0.10(Predicted)
form 
Powder
color 
Light beige
BRN 
2216
InChIKey
RSOPTYAZDFSMTN-UHFFFAOYSA-N
CAS DataBase Reference
6636-78-8(CAS DataBase Reference)
NIST Chemistry Reference
2-Chloro-3-pyridinol(6636-78-8)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-37/39-24/25-36
WGK Germany 
3
RTECS 
UU7707000
HazardClass 
IRRITANT
HS Code 
29333990

MSDS

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2-Chloro-3-hydroxypyridine Usage And Synthesis

Chemical Properties

light beige powder

Uses

2-Chloro-3-hydroxypyridine has been used in the preparation of 3-hydroxypyridine-2( 1 H)-selone. It has also been used in the synthesis of all four possible benzo[4,5]furopyridine tricyclic heterocycles: benzo[4,5]furo[2,3-b]pyridine, benzo[4,5]furo[2,3-c]pyridine, benzo[4,5]furo[3,2-c]pyridine, and benzo[4,5]furo[3,2-b]pyridine. the synthesis involves α and γ-activation of chloropyridines, as well as palladium-mediated reactions.

2-Chloro-3-hydroxypyridine Preparation Products And Raw materials

Preparation Products

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