5'-INOSINIC ACID DISODIUM SALT HYDRATE Chemical Properties

Melting point:

175 °C

storage temp. 

Inert atmosphere,2-8°C

solubility 

Aqueous Acid (Slightly), Water (Slightly)

form 

Solid

color 

White to Off-White

Stability:

Hygroscopic

InChIKey

CUKXPVZZLRNKJY-UYWZPSNANA-N

SMILES

O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O.[NaH].O |&1:1,2,3,11,r|

Safety Information

Hazard Codes 

Xn

Risk Statements 

62-33

Safety Statements 

36/37

WGK Germany 

2

RTECS 

NM7519500

F 

1-10

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS

5'-INOSINIC ACID DISODIUM SALT HYDRATE Usage And Synthesis

Description

Inosine-5''-monophosphate (IMP) is a substrate of IMP dehydrogenase (IMPDH), a NAD⁺-dependent enzyme that generates xanthosine monophosphate. This is a rate-limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. Inhibitors of IMPDH, including ribavirin (Item No. 16757) and mycophenolate mofetil (Item No. 13988), have potential applications as antiviral and anti-cancer drugs. 5-Ribonucleosides, including IMP, are also involved in potentiating the umami taste sensation.

Uses

Inosine-5''-monophosphate Sodium Salt Hydrate can be used for synthesis of fresh sauce for casserole. It is a sodium salt hydrate form of Inosine 5''-monophosphate (I665003), which can be used in combination with an immune checkpoint inhibitor for cancer immunotherapy.

5'-INOSINIC ACID DISODIUM SALT HYDRATE(20813-76-7)Related Product Information

• Inosine
• D-Fructose 1,6-bisphosphate trisodium salt
• IDP
• Inosine-5'-triphosphate trisodium salt
• IMP
• 2'-Deoxyinosine-5'-diphosphate, Disodium salt
• Inosine-5'-diphosphoric acid disodium salt
• 5'-INOSINIC ACID DISODIUM SALT HYDRATE
• 2'-Deoxyinosine 5'-monophosphate disodium salt
• Guanosine 5'-monophosphate disodium salt
• Disodium 5'-Inosinate