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(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol

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(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol Basic information

Product Name:
(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
Synonyms:
  • (7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol
  • Protosappanin B
  • (7S,12aS)-7,8-Dihydro-7-(hydroxymethyl)-6H-dibenz[b,d]oxocin-3,7,10,11-tetrol
  • 6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol,7,8-dihydro-7-(hydroxymethyl)-, (7S,12aS)-
  • FT-0689654
  • Q-100961
  • 6H-Dibenz[b,d]oxocin-3,7,10,11-tetrol,7,8-dihydro-7-(hydroxy...
CAS:
102036-29-3
MF:
C16H16O6
MW:
304.29
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
102036-29-3.mol
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(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol Chemical Properties

Boiling point:
655.5±55.0 °C(Predicted)
Density 
1.507
storage temp. 
2-8°C
pka
9.20±0.40(Predicted)
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(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanol Usage And Synthesis

Description

Research results in recent years have shown that sumac extract has a significant inhibitory effect on a variety of tumor cells. Protosappanin B is one of the main components in hematoxylin. It has inhibitory effect on the proliferation of both BTT and T24 cells, and as Protosappanin B acts on each cell for a longer period of time, its killing effect is gradually enhanced, showing a time-dependence.

Chemical Properties

Soluble in methanol, DMSO, insoluble in petroleum ether and other solvents.

Biological Activity

Protosappanin B is a polyphenol extracted from hematoxylin and has anti-tumor effects. In human bladder cancer cells, it can arrest the G1 phase of the cell cycle and induce apoptosis.

target

Apoptosis

(7S)-3,7,10,11-Tetrahydroxy-7,8-dihydro-6H-dibenzo[b,d]oxocin-7-methanolSupplier

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